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Elevated levels of high mobility group box chromosomal protein-1 (HMGB-1) in sera from patients with severe bacterial pneumonia coinfected with influenza virus.
http://hdl.handle.net/10069/22523
http://hdl.handle.net/10069/225238b4c5a3d-ed88-4c0c-84d6-9bf60f8dfc7e
名前 / ファイル | ライセンス | アクション |
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SJID40_338.pdf (266.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-11-30 | |||||
タイトル | ||||||
タイトル | Elevated levels of high mobility group box chromosomal protein-1 (HMGB-1) in sera from patients with severe bacterial pneumonia coinfected with influenza virus. | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HMGB-1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | influenza virus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | bacterial pneumonia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | co-infection | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kosai, Kosuke
× Kosai, Kosuke× Seki, Masafumi× Yanagihara, Katsunori× Nakamura, Shigeki× Kurihara, Shintaro× Izumikawa, Koichi× Kakeya, Hiroshi× Yamamoto, Yoshihiro× Tashiro, Takayoshi× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Plasma levels of high mobility group box chromosomal protein-1 (HMGB-1), as well as of other inflammatory molecules such as interleukin-6 (IL-6), regulated on activation normal T-cell expressed and secreted (RANTES), and soluble intercellular adhesion molecule-1 (sICAM-1), were determined in patients with bacterial pneumonia coinfected with influenza virus. HMGB-1 levels were significantly elevated in these patients compared to patients undergoing mild bacterial pneumonia alone (p < 0.01). Among cases of coinfection, we found a significant correlation between the concentration of HMGB-1 and white blood cell counts (p < 0.05, r = 0.612). Levels of IL-6 were also higher in these patients than in patients with bacterial pneumonia alone (p < 0.05), despite similar levels of RANTES and sICAM-1 in the 2 groups. These data suggest that HMGB-1 is involved in the pathogenesis of severe bacterial pneumonia coinfected with influenza virus. | |||||
書誌情報 |
Scandinavian journal of infectious diseases 巻 40, 号 4, p. 338-342, 発行日 2008 |
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出版者 | ||||||
出版者 | Taylor & Francis | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00365548 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1651-1980 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00833588 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 17918013 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1080/00365540701660486 | |||||
権利 | ||||||
権利情報 | c 2008 Informa UK Ltd. (lnforma Healthcare, Thylor & Francis As) | |||||
権利 | ||||||
権利情報 | This is an electronic version of an article published in Scandinavian journal of infectious diseases, 40(4), pp.338-342; 2008. Scandinavian Journal of Infectious Diseases is available online at: http://www.informaworld.comopenurl?genre=article&issn=0036-5548&volume=40&issue=4&spage=338. | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Scandinavian journal of infectious diseases, 40(4), pp.338-342; 2008 |