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Clinical Comparative Study of Sulbactam/Ampicillin and Imipenem/Cilastatin in Elderly Patients with Community-Acquired Pneumonia
http://hdl.handle.net/10069/22559
http://hdl.handle.net/10069/22559a0d11351-7bf4-40ce-ad1d-3789b3e72d53
名前 / ファイル | ライセンス | アクション |
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IM_45_17_995.pdf (636.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-12-04 | |||||
タイトル | ||||||
タイトル | Clinical Comparative Study of Sulbactam/Ampicillin and Imipenem/Cilastatin in Elderly Patients with Community-Acquired Pneumonia | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | community-acquired pneumonia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pulmonary infection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | clinical trial | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | elderly patients | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | antibiotics | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Yanagihara, Katsunori
× Yanagihara, Katsunori× Fukuda, Yuichi× Seki, Masafumi× Izumikawa, Koichi× Higashiyama, Yasuhito× Miyazaki, Yoshitsugu× Hirakata, Yoichi× Tomono, Kazunori× Mizuta, Yohei× Tsukamoto, Kazuhiro× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective: To evaluate the clinical usefulness of sulbactam/ampicillin therapy for community-acquired pneumonia in the elderly. Methodology: A randomized prospective clinical study was conducted in the elderly patients with moderate-to-severe community-acquired bacterial pneumonia. Results: Overall clinical efficacy of sulbactam/ampicillin therapy (6 g/day) in these patients (efficacy rate: 91.4%) was comparable to that of imipenem/cilastatin therapy (1 g/day; efficacy rate: 87.5%), when each therapy was administered intravenously twice daily for 7-14 days. With regard to clinical efficacy based on disease severity, bacteriological efficacy, improvement of chest X-ray findings and adverse reactions, the two therapies were comparable. Conclusion: These results suggest that sulbactam/ampicillin therapy has excellent efficacy and tolerability and that it may be highly effective, even in severe cases of pneumonia. This regimen may thus serve as first-line treatment for the treatment of community-acquired pneumonia in elderly patients. | |||||
書誌情報 |
Internal Medicine 巻 45, 号 17, p. 995-999, 発行日 2006-10 |
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出版者 | ||||||
出版者 | 日本内科学会 | |||||
出版者別言語 | ||||||
The Japanese Society of Internal Medicine | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09182918 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2169/internalmedicine.45.1717 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2006 (社)日本内科学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Internal Medicine, vol.45(17), pp.995-999; 2006 |