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A Clinical Comparative Study of Piperacillin and Sulbactam/Ampicillin in Patients with Community-Acquired Bacterial Pneumonia
http://hdl.handle.net/10069/22584
http://hdl.handle.net/10069/22584c80af4a1-63b5-4986-9f2f-7c0ee1b277c6
名前 / ファイル | ライセンス | アクション |
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IntMed48_49.pdf (889.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-12-04 | |||||
タイトル | ||||||
タイトル | A Clinical Comparative Study of Piperacillin and Sulbactam/Ampicillin in Patients with Community-Acquired Bacterial Pneumonia | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | community-acquired pneumonia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | antibiotics | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | clinical trials | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pulmonary infections | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Seki, Masafumi
× Seki, Masafumi× Higashiyama, Yasuhito× Imamura, Yoshifumi× Nakamura, Shigeki× Kurihara, Shintaro× Izumikawa, Koichi× Kakeya, Hiroshi× Yamamoto, Yoshihiro× Yanagihara, Katsunori× Tashiro, Takayoshi× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective To evaluate the clinical usefulness of piperacillin (4 g/day) therapy for community-acquired pneumonia compared to sulbactam/ampicillin (6 g/day). Methods A randomized prospective clinical study was conducted in patients with mild to severe community-acquired bacterial pneumonia. Results The overall clinical efficiency of piperacillin therapy (4 g/day) in these patients (41/53=77.4%) was comparable to that of sulbactam/ampicillin therapy (6 g/day: efficiency rate: 33/49=67.3%), when each therapy was administered intravenously for 3-7 days. With regards to clinical efficiency based on disease severity, bacteriological efficiency, improvement in chest X-ray findings and adverse reactions, the two therapies were comparable, even though we found more efficiency for patients who had underlying diseases and there were also cost benefits in piperacillin therapy, compared with sulbactam/ampicillin therapy Conclusion The results suggested that piperacillin therapy has good efficiency and tolerability and that it may be highly effective, even in cases of pneumonia with underlying diseases. This regimen may thus serve as a first line treatment of community-acquired pneumonia. | |||||
書誌情報 |
Internal Medicine 巻 48, 号 1, p. 49-55, 発行日 2009-01 |
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出版者 | ||||||
出版者 | 日本内科学会 | |||||
出版者別言語 | ||||||
The Japanese Society of Internal Medicine | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09182918 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2169/internalmedicine.48.1614 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2009 (社)日本内科学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Internal Medicine, 48(1), pp.49-55; 2009 |