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Population Polymorphism of Trypanosoma cruzi in Latin America indicated by Proteome analysis and by in vitro amastigote proliferation
http://hdl.handle.net/10069/21515
http://hdl.handle.net/10069/21515a3c34647-e779-4613-9073-e018e00cca88
名前 / ファイル | ライセンス | アクション |
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TMH34_167.pdf (617.2 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2009-04-09 | |||||
タイトル | ||||||
タイトル | Population Polymorphism of Trypanosoma cruzi in Latin America indicated by Proteome analysis and by in vitro amastigote proliferation | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Trypanosoma cruzi | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Two-dimensional gel electrophoresis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | in vitro amastigote proliferation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | genetic polymorphism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Latin America | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Mu, Jian-bing
× Mu, Jian-bing× Sone, Toshio× Yanagi, Tetsuo× Tada, Isao× Kikuchi, Mihoko× Hirayama, Kenji |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Nineteen stocks of Trypanosoma cruzi originating from several endemic countries for Chagas‘ disease in Central and South America were subjected to two-dimensional protein electrophoresis analysis. The presence or absence of a total of492polypeptide spots among19gel profiles was determined. The stocks were classified into three major distinctive groups derived from (I) Central America and the northern part of South America; (IIa) Central America and the northern part of South America; and (IIb) central and southern parts of South America, which showed perfect concordance with the previously reported classification based on isozyme and DNA sequence analyses. Late log phase of each epimastigote was inoculated to human cell lines WI-38and Hs224.T originating from the lung and muscle, respectively, and the number of trypomastigotes released was counted. The number of trypomastigotes from T. cruzi in group I released from the two cell lines was significantly higher than that in group III (p&It;0.05). The findings suggested that the phenetic distance appearing within the T. cruzi may, to some extent, be associated with the intracellular growth of T. cruzi, one of the characteristic features of growth found in the species. | |||||
書誌情報 |
Tropical medicine and health 巻 34, 号 4, p. 167-174, 発行日 2006-12 |
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出版者 | ||||||
出版者 | 日本熱帯医学会 | |||||
出版者 | ||||||
出版者 | The Japanese Society of Tropical Medicine | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13488945 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13494147 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11912848 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.2149/tmh.34.167 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2007 日本熱帯医学会 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Tropical Medicine and Health Vol. 34 No. 4, 2006, pp. 167-174 |