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Impact of Anatomical Resection for Hepatocellular Carcinoma With Microportal Invasion (vp1): A Multi-institutional Study by the Kyushu Study Group of Liver Surgery
http://hdl.handle.net/10069/39066
http://hdl.handle.net/10069/39066a61f1a35-138b-4ce4-9e63-e12127012c94
名前 / ファイル | ライセンス | アクション |
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AS_Hidaka2018.pdf (423.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2019-07-01 | |||||
タイトル | ||||||
タイトル | Impact of Anatomical Resection for Hepatocellular Carcinoma With Microportal Invasion (vp1): A Multi-institutional Study by the Kyushu Study Group of Liver Surgery | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatocellular carcinoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | liver resection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | portal venous invasion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | propensity score matching | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Hidaka, Masaaki
× Hidaka, Masaaki× Eguchi, Susumu× Okuda, Koji× Beppu, Toru× Shirabe, Ken× Kondo, Kazuhiro× Takami, Yuko× Ohta, Masayuki× Shiraishi, Masayuki× Ueno, Shinichi× Nanashima, Atsushi× Noritomi, Tomoaki× Kitahara, Kenji× Fujioka, Hikaru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective: The aim of the present study was to evaluate the value of anatomical resection for HCC with micro-portal vascular invasion (vp1) between 2000 and 2010. Summary of Background: Vascular invasion has been reported as a prognostic factor of liver resection for hepatocellular carcinoma (HCC). Anatomical resection for HCC has resulted in optimum outcomes of eradicating intrahepatic micrometastases through the portal vein, but opposite results have also been reported. Methods: A clinical chart review was performed for 546 HCC patients with vp1. We retrospectively evaluated the recurrence-free survival (RFS) between anatomical (AR)and non-anatomical resection (NAR). The site of recurrence was also compared between these groups. The influence of AR on the overall survival (OS) and RFS rates was analyzed in patients selected by propensity score matching, and the prognostic factors were identified. Results: A total of 546 patients were enrolled, including 422 in the AR group and 124 in the NAR group. There was no difference in the 5-year OS and RFS rates between the two groups. Local recurrence was significantly more frequent in the NAR group than in the AR group. In a multivariate analysis, hepatitis C (HCV), PIVKAII ?380 mAU/ml, tumor diameter ?5 cm and ?70 years of age were significant predictors of a poor RFS after liver resection. There were no significant differences in the OS or RFS between the AR and NAR groups by a propensity score-matched analysis. Conclusion: Although local recurrence around the resection site was suppressed by AR, AR for HCC with vp1 did not influence the RFS or OS rates after hepatectomy in the modern era. |
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書誌情報 |
Annals of Surgery 巻 271, 号 2, p. 339-346, 発行日 2018-07-01 |
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出版者 | ||||||
出版者 | Wolters Kluwer Health Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00034932 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1097/SLA.0000000000002981 | |||||
権利 | ||||||
権利情報 | c 2018 Wolters Kluwer Health, Inc. This is a non-final version of an article published in final form in Annals of Surgery, DOI: 10.1097/SLA.0000000000002981 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Annals of Surgery, 271(2), pp.339-346; 2020 |