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Thyroid Blockade during a Radiation Emergency in Iodine-rich Areas : Effect of a Stable-iodine Dosage
http://hdl.handle.net/10069/19135
http://hdl.handle.net/10069/19135b7fff14b-b82a-4260-b01a-335cfa9a1d8f
名前 / ファイル | ライセンス | アクション |
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RR45_2_201_204.pdf (431.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-08-12 | |||||
タイトル | ||||||
タイトル | Thyroid Blockade during a Radiation Emergency in Iodine-rich Areas : Effect of a Stable-iodine Dosage | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Thyroid gland | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Radiation emergency | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Iodine-rich areas | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Potassium iodide | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takamura, Noboru
× Takamura, Noboru× Nakamura, Yoshihiro× Ishigaki, Katsu× Ishigaki, Jitsuro× Mine, Mariko× Aoyagi, Kiyoshi× Yamashita, Shunichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We examined the effect of stable iodine on thyroid gland blockade in patients with hyperthyroidism in order to make a preliminary evaluation of the appropriate dose of iodine prophylaxis in the event of a radiation emergency in Japan in which radioiodine is released to the environment. Eight patients were orally given single doses of 50mg or 100mg of potassium iodide, which contained 38mg and 76mg of iodide, respectively. Both doses significantly suppressed a thyroid uptake of ^<123>I for 24 h (p=0.03). The protective effects at 24 h were 73.3% and 79.5%, respectively. No side effects were observed during the trial. The present study demonstrates that a single oral administration of 38mg of iodide produces a thyroid-blocking effect equivalent to that of 76mg of iodide, suggesting that a reevaluation of the stable iodine dosage during radiation emergencies in iodine-rich areas such as Japan is warranted. | |||||
書誌情報 |
Journal of radiation research 巻 45, 号 2, p. 201-204, 発行日 2004-06-15 |
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出版者 | ||||||
出版者 | 日本放射線影響学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 04493060 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00705792 | |||||
権利 | ||||||
権利情報 | 日本放射線影響学会 | |||||
権利 | ||||||
権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of radiation research. 2004, 45(2), p.201-204 |