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Tetrodotoxin - Distribution and accumulation in aquatic organisms, and cases of human intoxication
http://hdl.handle.net/10069/19193
http://hdl.handle.net/10069/1919316e17698-75a2-455e-96e3-be00655e3121
名前 / ファイル | ライセンス | アクション |
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MarDru6_220.pdf (433.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-08-18 | |||||
タイトル | ||||||
タイトル | Tetrodotoxin - Distribution and accumulation in aquatic organisms, and cases of human intoxication | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Gastropod | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Human intoxication | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Marine bacteria | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Newt | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pufferfish | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tetrodotoxin | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Noguchi, Tamao
× Noguchi, Tamao× Arakawa, Osamu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Many pufferfish of the family Tetraodontidae possess a potent neurotoxin, tetrodotoxin (TTX). In marine pufferfish species, toxicity is generally high in the liver and ovary, whereas in brackish water and freshwater species, toxicity is higher in the skin. In 1964, the toxin of the California newt was identified as TTX as well, and since then TTX has been detected in a variety of other organisms. TTX is produced primarily by marine bacteria, and pufferfish accumulate TTX via the food chain that begins with these bacteria. Consequently, pufferfish become non-toxic when they are fed TTX-free diets in an environment in which the invasion of TTX-bearing organisms is completely shut off. Although some researchers claim that the TTX of amphibians is endogenous, we believe that it also has an exogenous origin, i.e., from organisms consumed as food. TTX-bearing animals are equipped with a high tolerance to TTX, and thus retain or accumulate TTX possibly as a biologic defense substance. There have been many cases of human intoxication due to the ingestion of TTX-bearing pufferfish, mainly in Japan, China, and Taiwan, and several victims have died. Several cases of TTX intoxication due to the ingestion of small gastropods, including some lethal cases, were recently reported in China and Taiwan, revealing a serious public health issue. | |||||
書誌情報 |
Marine Drugs 巻 6, 号 2, p. 220-242, 発行日 2008-06 |
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出版者 | ||||||
出版者 | Molecular Diversity Preservation International | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 16603397 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/md20080011 | |||||
権利 | ||||||
権利情報 | c 2008 by the author(s). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Marine Drugs, 6(2), pp.220-242; 2008 |