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Molecular epidemiology of dengue 2 viruses in the Philippines: genotype shift and local evolution.
http://hdl.handle.net/10069/20114
http://hdl.handle.net/10069/20114a9163c81-63d1-4725-bfb9-ad4ab2c8f690
名前 / ファイル | ライセンス | アクション |
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ajtmh73_796.pdf (455.6 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-10-21 | |||||
タイトル | ||||||
タイトル | Molecular epidemiology of dengue 2 viruses in the Philippines: genotype shift and local evolution. | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Salda, Leonora T. D.
× Salda, Leonora T. D.× Parquet, Maria D. C.× Matias, Ronald R.× Natividad, Filipinas F.× Kobayashi, Noboyuki× Morita, Kouichi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The pre-membrane (prM) and envelope (E) genes of 41 viruses isolated from dengue fever (DF), dengue hemorrhagic fever (DHF), and dengue shock syndrome (DSS) patients from 1995 to 2002 were sequenced to determine the genetic variability of dengue 2 (DENV 2) viruses in the Philippines. The envelope sequence data were compared with a global sample of DENV 2 obtained from GenBank. Phylogenetic analysis revealed that two distinct genotypes, Asian 2 and Cosmopolitan, are currently circulating locally, each with the potential to cause severe hemorrhagic disease. After the initial isolation in 1998, the Cosmopolitan genotype has gradually and effectively replaced Asian genotype 2 in the Philippines. Members of this genotype were closely related to viruses from Australia, Singapore, and Thailand. | |||||
書誌情報 |
American Journal of Tropical Medicine and Hygiene 巻 73, 号 4, p. 796-802, 発行日 2005-10 |
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出版者 | ||||||
出版者 | American Society of Tropical Medicine and Hygiene | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00029637 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00521439 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 16222028 | |||||
権利 | ||||||
権利情報 | Copyright (c) 2005 by The American Society of Tropical Medicine and Hygiene | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://www.ajtmh.org/cgi/content/abstract/73/4/796 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | American Journal of Tropical Medicine and Hygiene, 73(4), pp.796-802; 2005 |