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塩酸イリノテカンによると思われる薬剤性肺臓炎の1例
http://hdl.handle.net/10069/20263
http://hdl.handle.net/10069/2026393271483-6c17-46ee-b8df-4d0652843e2b
名前 / ファイル | ライセンス | アクション |
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haigan39_1_57_61.pdf (1.1 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-11-19 | |||||
タイトル | ||||||
タイトル | 塩酸イリノテカンによると思われる薬剤性肺臓炎の1例 | |||||
言語 | ||||||
言語 | jpn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | CPT-11 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Drug-induced pneumonitis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Small cell lung cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cancer chemotherapy | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
鶴谷, 純司
× 鶴谷, 純司× 福田, 実× 福田, 正明× 高谷, 洋× 岡三, 喜男× 河野, 茂 |
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著者別名 | ||||||
姓名 | Tsurutani, Junji | |||||
著者別名 | ||||||
姓名 | Fukuda, Minoru | |||||
著者別名 | ||||||
姓名 | Fukuda, Masaki | |||||
著者別名 | ||||||
姓名 | Takatani, Hiroshi | |||||
著者別名 | ||||||
姓名 | Oka, Mikio | |||||
著者別名 | ||||||
姓名 | Kohno, Shigeru | |||||
その他のタイトル | ||||||
その他のタイトル | A Case of Drug-induced PneumonitisProbably Due to Irinotecan Hydrochloride | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 51歳,男性の進展型肺小細胞癌(T2N3M1)に対しシスプラチンとエトポシドの併用化学療法を2コース施行し,引き続いて塩酸イリノデカン(以下CPT-11)を総計560mg(320mg/m2)投与した.CPT-11投与開始後7週目より乾性咳鰍と38℃台の発熱を認め,胸部レントゲン写真で両下肺野を中心にスリガラス様陰影,胸部CTでは両肺びまん性の肺野濃度上昇を認めた.臨床経過よりCPT-11による肺臓炎を疑い,静注メチルプレドニゾロンおよび経口プレドニソロンを投与し,臨床症状の軽快と胸部レントゲン写真およびCTで陰影の改善を認めた.CPT-11による薬剤性肺臓炎の報告は少ないが,今後CPT-11を投与するにあたり十分な注意と発症時の早急な対処が必要である. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A 51-year-old patient with extensive small cell lung cancer was treated with a total of 560mg ( 320mg/m2 ) of irinotecan hydrochloride ( CPT-1 1 ) following two cycles of cisplatin and etoposide. In the seventh week after the start of CPT-11 therapy, the patient complained of hacking cough and exertional dyspnea with a high fever. Chest X-ray film and chest computed tomogram showed ground-glass opacity mainly in both lower lung fields. Drug-induced pneumonitis due to CPT-11 was strongly suspected, and prednisolone was orally administered and methylprednisolone was administered intravenously. After the steroid therapy, the symptoms and lung opacity gradually disappeared. Although CPT-11-induced pneumonitis is rare, oncologists should be aware of the possibility of its occurring during or following CPT-11 administration. | |||||
書誌情報 |
肺癌 en : Japanese Journal of Lung Cancer 巻 39, 号 1, p. 57-61, 発行日 1999-02-20 |
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出版者 | ||||||
出版者 | 日本肺癌学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03869628 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00203978 | |||||
権利 | ||||||
権利情報 | 日本肺癌学会 | |||||
権利 | ||||||
権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 肺癌 = Japanese Journal of Lung Cancer, 39(1), p.57-61; 1999 |