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A Study on the Expression of EGFR and c-erbB-2 and Nuclear DNA Content in the Stomach Cancer Tissue
http://hdl.handle.net/10069/17574
http://hdl.handle.net/10069/17574891f8e49-24ae-4a6d-9dd3-838de4a7a4dd
名前 / ファイル | ライセンス | アクション |
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acta37_01-04_29_t.pdf (1.9 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-06-20 | |||||
タイトル | ||||||
タイトル | A Study on the Expression of EGFR and c-erbB-2 and Nuclear DNA Content in the Stomach Cancer Tissue | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Nakazaki, Takayuki
× Nakazaki, Takayuki |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The expression of EGFR and c-erbB-2 as well as the measurement of nuclear DNA content was evaluated in stomach cancer tissues. In addition, changes in the expression of EGFR in stomach cancer cells in mixed culture with lymphocytes were also studied by flowcytometry. The frequencies of expression of EGFR and c-erb B-2 and of the aneuploid pattern in analysis of nuclear DNA content were 35.5% and 59.3%, in the primary focus respectively. By histological types, the rates of positive c-erbB-2 expression and the appearance of aneuploidy were high in differentiated cancer, while the EGFR expression rate showed no difference according to histological types. As to lymph node metastasis, the involvement of the lymph nodes in EGFR-positive cases was more significant than that in EGFR-negative viz. 86.4% vs. 43.2%. On the other hand, the attitude of EGFR expression was clearly altered when stomach cancer cells were incubated with lymphocytes. It is possible to draw the conclusion that the weaker the expression of EGFR in stomach cancer cells, the greater the susceptibility to lymphocytes in gastric cancer cells. | |||||
書誌情報 |
Acta Medica Nagasakiensia 巻 37, 号 1/4, p. 133-137, 発行日 1992-12-25 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00133-P00127 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta Medica Nagasakiensia. 1992, 37(1-4), p.133-137 |