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Changes in Serum Granulocyte Colony-Stimulating Factor Concentration after Gastrointestinal Surgery
http://hdl.handle.net/10069/16053
http://hdl.handle.net/10069/160537c63087a-21a6-4257-8238-b05c735e4325
名前 / ファイル | ライセンス | アクション |
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acta41_01_10_t.pdf (377.7 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | Changes in Serum Granulocyte Colony-Stimulating Factor Concentration after Gastrointestinal Surgery | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gastrointestinal surgery | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | granulocyte colonystimulating factor | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Noguchi, Takayuki
× Noguchi, Takayuki× Mori, Masakazu× Yoshitake, Sigenori× Kitano, Takaaki× Miyakawa, Hiroshi× Honda, Natsuo |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Granulocyte colony-sitmulating factor (G-CSF ; normal range < 30 pg/ml) is a cytokine that stimulates the proliferation and activation of neutrophils. In this study, we investigated changes in the plasma G-CSF level after gastrointestinal surgery. The subjects were 23 patients undergoing subtotal esophagectomy (Group E, n = 8), pancreaticoduodenectomy (Group P, n = 5), radical total gastrectomy (Group G, n = 5), or cholecystectomy (Group C, n = 5). In addition to G-CSF, duration of surgery, transfused fluid volume, C-reactive protein (CRP) concentration and neutrophil counts were recorded. G-CSF levels just after surgery were 3,301±2,130 pg/ml (mean ±SD), 1,442±180 pg/ml, 941 ±538 pg/ml, and 111±73pg/ml for patients in proups E, P, G and C, respectively. G-CSF levels were correlated with postoperative maximum CRP, the duration of surgery and the transfused fluid volume during the operation. The results show that extensive surgical procedures are associated with higher postoperative plasma G-CSF levels, suggesting that the increase in plasma G-CSF may be due to activation of the host defense in response to surgical stress. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 41, 号 1-2, p. 67-70, 発行日 1996-06-20 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00067-P00070 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1996, 41(1-2), p.67-70 |