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Detection of Epstein-Barr Virus and Helicobacter pylori in Primary Malignant Gastric Lymphomas
http://hdl.handle.net/10069/16120
http://hdl.handle.net/10069/1612038dfab9a-20c3-4115-933d-b1dbb71d4e35
名前 / ファイル | ライセンス | アクション |
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acta43_03_11_t.pdf (1.9 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | Detection of Epstein-Barr Virus and Helicobacter pylori in Primary Malignant Gastric Lymphomas | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | primary gastric malignant lymphoma (PGML) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Epstein-Barr virus (EBV) Helicobacter pylori (H.pylori) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | in situ hybridization (ISH) | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Shikuwa, Saburo
× Shikuwa, Saburo× Matsunaga, Keiichiro× Isomoto, Hajime× Osabe, Masayuki× Takehara, Yusuke× Ofukuji, Megumi× Yoshimura, Masaya× Ito, Akira× Simokawa, Isao× Ito, Masahiro× Murase, Kunihiko× Takeshima, Fuminao× Omagari, Katsuhisa× Mizuta, Yohei× Kohno, Shigeru |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | We studied five patients diagnosed with primary gastric lymphoma between 1985 and 1995 in Omura Munisipa Hospital to investigate the relationship between Helicobacter pylori, Epstein-Barr virus and primary malignant gastric lymphoma. H. pylori was detected by hematoxylin-eosin stain, Giemsa stain, immunohistochemistry while EBV was detected by in situ hybridization in the lymphoma and background mucosa. H. pylori but not EBV, was detected in all cases. Furthermore, malignant lymphomas were mainly located in the area of the fundic gland where H. pylori was frequently identified and caused inflammation. In contrast, malignant lymphomas were not detected in areas with intestinal metaplasia. Our results suggest that malignant lymphoma may develop in a region where the immune system has been activated by H. pylori. In contrast, EBV is unlikely to play an important role in the development of gastric lymphoma, compared to H. pylori. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 43, 号 3-4, p. 72-78, 発行日 1998-12-16 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00072-P00078 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1998, 43(3-4), p.72-78 |