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Antineutrophil Cytoplasmic Antibody-associated Vasculitis Complicating Graves' Disease: Report of Two Adult Cases
http://hdl.handle.net/10069/16155
http://hdl.handle.net/10069/16155a3e27ae4-7fdc-4c72-956b-ad5f9472c36a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
acta45_01_05_t.pdf (437.7 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
|---|---|---|---|---|---|---|
| 公開日 | 2008-03-13 | |||||
| タイトル | ||||||
| タイトル | Antineutrophil Cytoplasmic Antibody-associated Vasculitis Complicating Graves' Disease: Report of Two Adult Cases | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA ) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | vasculitis | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | propylthiouracil (PTU) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | Graves' disease | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Sera, Nobuko
× Sera, Nobuko× Yokoyama, Naokata× Abe, Yasuyo× Ide, Akane× Usa, Toshirou× Tominaga, Tan× Ejima, Eri× Kawakami, Atsushi× Ashizawa, Kiyoto× Eguchi, Katsumi |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | Two adult female patients with established Graves' disease were treated with propylthiouracil (PTU). One patient developed agranulocytosis, high fever of unknown origin and bilateral episcleritis. Another patient reported repeated attacks of common cold-like symptoms, polyarthralgia and skin purpura. There was no hematuria or proteinuria. Administration of PTU was withdrawn following identification of high myeloperoxidase-antineutrophil cytoplasmic antibody (MPO-ANCA) titer in the serum. Without steroids or immunosuppressive therapy, symptoms improved gradually in association with a fall in serum MPO-ANCA titer. We speculated that the symptoms of our two cases were due to MPO-ANCA associated vasculitis. MPO-ANCA positive vasculitis and glomerulonephritis are rare complications of PTU therapy, however, when these occur, the condition may become serious. Patients with Graves' disease treated with PTU should be carefully observed during therapy. | |||||
| 書誌情報 |
Acta medica Nagasakiensia 巻 45, 号 1-2, p. 33-36, 発行日 2000-06-14 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00016055 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508430 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| sortkey | ||||||
| 値 | P00033-P00036 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Acta medica Nagasakiensia. 2000, 45(1-2), p.33-36 | |||||
