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Immunohistochemical Study on Wound Healing of a Muscle Flap Transferred into the Oral Cavity of Rats
http://hdl.handle.net/10069/16727
http://hdl.handle.net/10069/167271459a31e-9c3f-4e41-8dbb-eb9b48d031be
名前 / ファイル | ライセンス | アクション |
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OMP6_1_29.pdf (2.3 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2008-04-28 | |||||
タイトル | ||||||
タイトル | Immunohistochemical Study on Wound Healing of a Muscle Flap Transferred into the Oral Cavity of Rats | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | contraction | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | myofibroblast | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fibroblast growth factor-2 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fibroblast growth factor receptor-1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fibroblast growth factor receptor-2 | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tobita, Takayoshi
× Tobita, Takayoshi× Inokuchi, Tsugio |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The immunohistochemical expressions of FGF2, FGFRL FGFR2, and their possible participation in the apoptosis of myofibroblast were studied in the healing process of a muscle flap transferred into the oral cavity of rats. At 14 days postoperatively, abundant myofibroblasts were observed in the early-granulating muscle flap, and at 18 days postoperatively, they began to gradually disappear. The FGF2 immunopositive area, the number of FGFR2-positive fibroblasts and TUNEL-positive fibroblasts reached a maximum at 18 days postoperatively and gradually decreased thereafter, and there was a significant correlation of expression between the FGFR2- positive fibroblast and TUNEL-positive fibroblast. On the other hand, FGFR1-positive fibroblasts were observed from day 10 to 21 in the granulation tissue formation of the muscle flap. These findings suggest that FGFR1 may participate as a factor affecting tissue remodeling of muscle flap healing, and that FGFR2 may play a role in programmed cell death or apoptosis of myofibroblast. | |||||
書誌情報 |
Oral medicine & pathology 巻 6, 号 1, p. 29-36, 発行日 2001-06-30 |
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出版者 | ||||||
出版者 | 日本口腔病理学会 | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13420984 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11097826 | |||||
権利 | ||||||
権利情報 | 日本口腔病理学会 | |||||
権利 | ||||||
権利情報 | 本文データは学協会の許諾に基づきCiNiiから複製したものである | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Oral medicine & pathology. 2001, 6(1), p.29-36 |