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Human antibody response to dengue virus: implications for dengue vaccine design
http://hdl.handle.net/10069/37291
http://hdl.handle.net/10069/3729108c6b727-6f2b-4b2a-8edd-84425aaaf310
名前 / ファイル | ライセンス | アクション |
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TMH44_1.pdf (479.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-05-16 | |||||
タイトル | ||||||
タイトル | Human antibody response to dengue virus: implications for dengue vaccine design | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Antibody-dependent enhancement | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Dengue virus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Disease protection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | FcgammaR-expressing cells | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Vaccine | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Moi, Meng Ling
× Moi, Meng Ling× Takasaki, Tomohiko× Kurane, Ichiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Dengue, a global health threat, is a leading cause of morbidity and mortality in most tropical and subtropical countries. Dengue can range from asymptomatic, relatively mild dengue fever to severe and life-threatening dengue hemorrhagic fever. Disease severity and outcome is largely associated with the host immune response. Several candidate vaccines in clinical trials appear promising as effective measures for dengue disease control. Vaccine development has been hampered by safety and efficacy issues, driven by a lack of understanding of the host immune response. This review focuses on recent research findings on the dengue host immune response, particularly in humans, and the relevance of these findings to challenges in vaccine development. | |||||
書誌情報 |
Tropical Medicine and Health 巻 44, p. 1, 発行日 2016-03-14 |
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出版者 | ||||||
出版者 | 日本熱帯医学会 | |||||
出版者別言語 | ||||||
Japanese Society of Tropical Medicine | ||||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13494147 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/s41182-016-0004-y | |||||
権利 | ||||||
権利情報 | c Moi et al 2016 | |||||
権利 | ||||||
権利情報 | This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Tropical Medicine and Health, 44, 1; 2016 |