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Height indicates hematopoietic capacity in elderly Japanese men
http://hdl.handle.net/10069/37355
http://hdl.handle.net/10069/373555b41e0b7-bbac-48d1-b8b6-f4b2f4d59e1d
名前 / ファイル | ライセンス | アクション |
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Aging8_2407.pdf (590.9 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-05-25 | |||||
タイトル | ||||||
タイトル | Height indicates hematopoietic capacity in elderly Japanese men | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Elderly men | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Height | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hematopoiesis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Reticulocyte | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Shimizu, Yuji
× Shimizu, Yuji× Sato, Shimpei× Koyamatsu, Jun× Yamanashi, Hirotomo× Nagayoshi, Mako× Kadota, Koichiro× Maeda, Takahiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Previously, we reported that height is an indicator of the capacity of vascular repair in elderly men, especially hypertensive men. On the other hand, hemoglobin could act as a possible biochemical index of hypertensioninduced vascular damage. However, no studies have clarified the correlation between height and hematopoietic activity. We conducted a cross-sectional study of 249 men aged 65-69 undergoing a general health check-up. Reticulocyte was used to evaluate hematopoietic activity. Because hemoglobin concentration should influence hematopoietic activity, analyses stratified by hemoglobin level were performed. Independent of known cardiovascular risk factors and other hematological parameters (white blood cell count), a significant positive correlation was seen between height and reticulocytes for total subjects and subjects with a high hemoglobin concentration (?14.5 g/dL), but not in subjects with a low hemoglobin concentration (<14.5 g/dL). The standardized parameter estimates (β) were β=0.18, p=0.003 for total subjects, β=0.28, p=0.001 for subjects with a high hemoglobin concentration, and β=0.03, p=0.717 for subjects with low hemoglobin. Independently, height is significantly positively correlated with reticulocyte in elderly Japanese men, particularly in men with a high hemoglobin concentration. These results indicate that subjects with a short stature might have lower hematopoietic capacity than those with a high stature. | |||||
書誌情報 |
Aging 巻 8, 号 10, p. 2407-2413, 発行日 2016-10-04 |
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出版者 | ||||||
出版者 | Impact Journals LLC | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 19454589 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.18632/aging.101061 | |||||
権利 | ||||||
権利情報 | c 2016 Impact Journals, LLC | |||||
権利 | ||||||
権利情報 | This is an open access article under the terms of the Creative Commons Attribution License (CC BY). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Aging, 8(10), pp.2407-2413; 2016 |