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Ultrastructural Study of the Dorsal Root Ganglia in Fetal Organic Mercury Intoxicated Rats
http://hdl.handle.net/10069/15596
http://hdl.handle.net/10069/155966f73fa3b-88d2-457b-b8ef-559a473a70a1
名前 / ファイル | ライセンス | アクション |
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acta22_01_02_t.pdf (4.1 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-10 | |||||
タイトル | ||||||
タイトル | Ultrastructural Study of the Dorsal Root Ganglia in Fetal Organic Mercury Intoxicated Rats | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Kishikawa, Masao
× Kishikawa, Masao |
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著者別名 | ||||||
姓名 | 岸川, 正大 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Methylmercuric chloride (MeHg) was given in pregnant rats during the last week of gestation. Newborn and infant rats treated with MeHg during intrauterine life were sacrificed at birth, and 5th, 10th and 30th day after birth. Dorsal root ganglia (DRG) of the baby rats were examined light and electron microscopically. The neurons were more various in shape and had eccentric nuclei more often than these in control baby rats. Interface between the neurons and their satellite cells showed less interdigitations even at 30 days of age. The rough endoplasmic reticulum (RER) was shortened with dilated cisternae and irregular branching. At 30-day-old rat, the dilated endoplasmic reticulum was decreased in number. The alterations of RER are an evidence of morphological aspects for the protein synthesis decreasing. By 10th day, the neurofibrils were not so prominent in DRG neurons of MeHg treated rat at 5th day, while they were increased in number to form fibrillar bundle and separated the RER into small stacks at 30 days of age. This may reflect early, ongoing regenerative changes in injured DRG neurons. The DRG from the MeHg-baby rats disclosed extensive injuries of neurons, associated with developmental retardation of the ganglia. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 22, 号 1-2, p. 50-62, 発行日 1977-10-25 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00050-P00062 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1977, 22(1-2), p.50-62 |