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Studies on the Effects of Growth Hormone on the Retinal Vascular Elements of Streptozotocin Induced Diabetic Rats
http://hdl.handle.net/10069/15635
http://hdl.handle.net/10069/15635454419b7-fcdb-40c2-a824-16369345d530
名前 / ファイル | ライセンス | アクション |
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acta26_01_08_t.pdf (2.6 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-10 | |||||
タイトル | ||||||
タイトル | Studies on the Effects of Growth Hormone on the Retinal Vascular Elements of Streptozotocin Induced Diabetic Rats | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Tsuda, Naoyuki
× Tsuda, Naoyuki× Takaku, Isao |
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著者別名 | ||||||
姓名 | 津田, 尚幸 | |||||
著者別名 | ||||||
姓名 | 高久, 功 | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The morphologically characteristic changes were irregular thickening of the basement membrane in the streptozotocin induced diabetic group (S rats) and more striking irregular hypertrophy of the same membrane in the group further administered with growth hormone (S+BGH rats). In the outer basement membrane surrounding the pericytes of S rats and S+BGH rats retinal capillary, and deposit of elastine could be suggested, which were seen as electron lucid, were proved by tannic acid stainning to be substances with high electron density. Biochemical assay disclosed that the characteristic change was a marked increase in hydroxyproline in the group with diabetes and an increase in hexosamine and also in sialic acid in the group further administrated with growth hormone. In view of the above finding, it was considered that substances of the collagen group are involved in the thickening of the basement membrane in diabetes, and that the loading with growth hormone is influential on glycoproteins deposition. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 26, 号 1-4, p. 73-81, 発行日 1981-10-25 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00073-P00081 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1981, 26(1-4), p.73-81 |