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The Optimum Colloid Osmotic Pressure for Lung Preservation -A hyperoncotic solution which contains a high concentration of hydroxyethyl starch (HES) prevents pulmonary edema during preservation and reperfusion periods in hypothermic canine lung preservation -
http://hdl.handle.net/10069/15979
http://hdl.handle.net/10069/15979ca9905cf-10b3-448d-81e6-70667ef37f94
名前 / ファイル | ライセンス | アクション |
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acta39_01_18_t.pdf (687.9 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2008-03-13 | |||||
タイトル | ||||||
タイトル | The Optimum Colloid Osmotic Pressure for Lung Preservation -A hyperoncotic solution which contains a high concentration of hydroxyethyl starch (HES) prevents pulmonary edema during preservation and reperfusion periods in hypothermic canine lung preservation - | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Muraoka, Masashi
× Muraoka, Masashi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The optimum hydroxyethyl starch (HES) concentration and colloid osmotic (oncotic) pressure were determined for lung preservation. The lungs of twenty-five mongrel dogs were isolated and flushed with one of four different solutions and stored at 4-6 °C for 24 hours. The lungs of each group were flushed and cold-stored as follows: Group 1 with Modified- Collins (CM) solution (n=6); Group 2, CM + 3 % HES (n=6); Group 3, CM +6 % HES (n=8); Group 4, CM + 9 % HES (n=5). After the hypothermic period, the isolated left lung was reperfused for 120 min. During reperfusion, the airway pressure (AWP) in Group 4 was significantly lower than in Groups 1 or 3. Static lung compliance (Cst) in Groups 2 and 4 was apparently higher than that in Group 1. Pulmonary vascular resistance (PVR) in Group 4 was significantly lower than in Group 1 throughout the reperfusion period. The wet to dry ratios (W/D) before perfusion in Group 1 (6.52±0.55) and in Group 2 (6.05±0.74) were significantly higher than before preservation (5.19±0.21). The W/Ds after reperfusion in Group 3 (6.82±0.78) and Group 4 (7.04±1.22) were significantly lower than that in Group 1 (9.40±2.09). In conclusion, a hyperoncotic solution which contains a high concentration of HES is useful for hypothermic canine lung preservation because it prevents pulmonary edema during both preservation and reperfusion periods. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 39, 号 1-3, p. 94-99, 発行日 1994-10-25 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
sortkey | ||||||
P00094-P00099 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia. 1994, 39(1-3), p.94-99 |