WEKO3
アイテム
{"_buckets": {"deposit": "3793c5c8-a0bc-41a3-9c54-1face5d017cf"}, "_deposit": {"created_by": 2, "id": "23160", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "23160"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00023160", "sets": ["74"]}, "author_link": ["97770", "97771", "97772", "97773", "97774"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2001-12", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "12", "bibliographicPageEnd": "1445", "bibliographicPageStart": "1443", "bibliographicVolumeNumber": "24", "bibliographic_titles": [{"bibliographic_title": "Biological \u0026 Pharmaceutical Bulletin"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The MeOH extract of the seeds of Rhynchosia volubilis (Leguminosae) showed antiproliferative activity against human gastric adenocarcinoma [MK-1, 50% growth inhibition (GI50): 25 μg/ml], human uterus carcinoma (HeLa, GI50: 30 μg/ml), and murine melanoma (B16F10, GI50: 8 μg/ml) cells. Bioactivity-guided fractionation resulted in the isolation of gallic acid methylester (1), gallic acid (2), 7-O-galloylcatechin (3), 1,6-di-O-galloylglucose (4), 1-O-galloylglucose (5), and trigalloylgallic acid (6), and their antiproliferative activity was estimated. All showed much stronger inhibition against B16F10 cell growth than against HeLa and MK-1 cell growth. Compound 2 and its tetramer (6) with a free carboxyl group showed higher activity than those which did not have a free carboxyl group. In relation to the gallic acid tetramer (6), two gallic acid dimers (ellagic acid and dehydrodigallic acid) and trimers (tergallic acid dilactone and flavogallonic acid dilactone) were tested for their activity, and compared with those of the isolates.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Biological \u0026 Pharmaceutical Bulletin v.24(12) p.1443-1445, 2001", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Pharmaceutical Society of Japan"}]}, "item_2_relation_11": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "11767121", "subitem_relation_type_select": "PMID"}}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1248/bpb.24.1443", "subitem_relation_type_select": "DOI"}}]}, "item_2_relation_42": {"attribute_name": "関係URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "http://dx.doi.org/10.1248/bpb.24.1443"}]}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10885497", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "09186158", "subitem_source_identifier_type": "ISSN"}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1347-5215", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Kinjo, Junei"}], "nameIdentifiers": [{"nameIdentifier": "97770", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagao, Tsuneatsu"}], "nameIdentifiers": [{"nameIdentifier": "97771", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "97772", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nonaka, Gen-Ichiro"}], "nameIdentifiers": [{"nameIdentifier": "97773", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okabe, Hikaru"}], "nameIdentifiers": [{"nameIdentifier": "97774", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BPBul24_1443.pdf", "filesize": [{"value": "51.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 51300.0, "url": {"label": "BPBul24_1443.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/23160/files/BPBul24_1443.pdf"}, "version_id": "e09745d7-b471-46e2-86b3-7d73a65e1c2d"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Rhynchosia volubilis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "antiproliferative activity", "subitem_subject_scheme": "Other"}, {"subitem_subject": "polyphenol", "subitem_subject_scheme": "Other"}, {"subitem_subject": "gallic acid and related compound", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Antiproliferative Constituents in the Plant 8. Seeds of Rhynchosia volubilis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Antiproliferative Constituents in the Plant 8. Seeds of Rhynchosia volubilis"}]}, "item_type_id": "2", "owner": "2", "path": ["74"], "permalink_uri": "http://hdl.handle.net/10069/8375", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-10-12"}, "publish_date": "2007-10-12", "publish_status": "0", "recid": "23160", "relation": {}, "relation_version_is_last": true, "title": ["Antiproliferative Constituents in the Plant 8. Seeds of Rhynchosia volubilis"], "weko_shared_id": -1}
Antiproliferative Constituents in the Plant 8. Seeds of Rhynchosia volubilis
http://hdl.handle.net/10069/8375
http://hdl.handle.net/10069/8375d58628d5-0966-4ca4-b6a1-1799bd37d9d4
名前 / ファイル | ライセンス | アクション |
---|---|---|
BPBul24_1443.pdf (51.3 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2007-10-12 | |||||
タイトル | ||||||
タイトル | Antiproliferative Constituents in the Plant 8. Seeds of Rhynchosia volubilis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Rhynchosia volubilis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | antiproliferative activity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | polyphenol | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | gallic acid and related compound | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kinjo, Junei
× Kinjo, Junei× Nagao, Tsuneatsu× Tanaka, Takashi× Nonaka, Gen-Ichiro× Okabe, Hikaru |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The MeOH extract of the seeds of Rhynchosia volubilis (Leguminosae) showed antiproliferative activity against human gastric adenocarcinoma [MK-1, 50% growth inhibition (GI50): 25 μg/ml], human uterus carcinoma (HeLa, GI50: 30 μg/ml), and murine melanoma (B16F10, GI50: 8 μg/ml) cells. Bioactivity-guided fractionation resulted in the isolation of gallic acid methylester (1), gallic acid (2), 7-O-galloylcatechin (3), 1,6-di-O-galloylglucose (4), 1-O-galloylglucose (5), and trigalloylgallic acid (6), and their antiproliferative activity was estimated. All showed much stronger inhibition against B16F10 cell growth than against HeLa and MK-1 cell growth. Compound 2 and its tetramer (6) with a free carboxyl group showed higher activity than those which did not have a free carboxyl group. In relation to the gallic acid tetramer (6), two gallic acid dimers (ellagic acid and dehydrodigallic acid) and trimers (tergallic acid dilactone and flavogallonic acid dilactone) were tested for their activity, and compared with those of the isolates. | |||||
書誌情報 |
Biological & Pharmaceutical Bulletin 巻 24, 号 12, p. 1443-1445, 発行日 2001-12 |
|||||
出版者 | ||||||
出版者 | Pharmaceutical Society of Japan | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09186158 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1347-5215 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10885497 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 11767121 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/bpb.24.1443 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://dx.doi.org/10.1248/bpb.24.1443 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Biological & Pharmaceutical Bulletin v.24(12) p.1443-1445, 2001 |