WEKO3
アイテム
{"_buckets": {"deposit": "07da8754-589a-4e61-a691-eff3341b18ac"}, "_deposit": {"created_by": 2, "id": "23172", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "23172"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00023172", "sets": ["74"]}, "author_link": ["97847", "97849", "97848", "97851", "97850", "97846"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2004-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "255", "bibliographicPageStart": "251", "bibliographicVolumeNumber": "27", "bibliographic_titles": [{"bibliographic_title": "Biological \u0026 Pharmaceutical Bulletin"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Eighteen main compounds, including four norsesquiterpenoids (1?4) and 14 phenolic compounds (5?18) isolated previously from Phyllanthus emblica, together with a main constituent, proanthocyanidin polymers (19) identified at this time from the roots, were estimated for their antiproliferative activities against MK-1 (human gastric adenocarcinoma), HeLa (human uterine carcinoma), and B16F10 (murine melanoma) cells using an MTT method. All of the phenolic compounds including the major components 5?8 from the fruit juice, 8, 9, and 12 from the branches and leaves, and 19 from the roots showed stronger inhibition against B16F10 cell growth than against HeLa and MK-1 cell growth. Norsesquiterpenoid glycosides 3 and 4 from the roots exhibited significant antiproliferative activities, although their aglycon 1 and monoglucoside 2 showed no inhibitory activity against these tumor cells.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Biological \u0026 Pharmaceutical Bulletin v.27(2) p.251-255, 2004", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Pharmaceutical Society of Japan"}]}, "item_2_relation_11": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "14758047", "subitem_relation_type_select": "PMID"}}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1248/bpb.27.251", "subitem_relation_type_select": "DOI"}}]}, "item_2_relation_42": {"attribute_name": "関係URI", "attribute_value_mlt": [{"subitem_relation_name": [{"subitem_relation_name_text": "http://dx.doi.org/10.1248/bpb.27.251"}]}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA10885497", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "09186158", "subitem_source_identifier_type": "ISSN"}]}, "item_2_source_id_8": {"attribute_name": "EISSN", "attribute_value_mlt": [{"subitem_source_identifier": "1347-5215", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Zhang, Ying-Jun"}], "nameIdentifiers": [{"nameIdentifier": "97846", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagao, Tsuneatsu"}], "nameIdentifiers": [{"nameIdentifier": "97847", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Takashi"}], "nameIdentifiers": [{"nameIdentifier": "97848", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yang, Chong-Ren"}], "nameIdentifiers": [{"nameIdentifier": "97849", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Okabe, Hikaru"}], "nameIdentifiers": [{"nameIdentifier": "97850", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kouno, Isao"}], "nameIdentifiers": [{"nameIdentifier": "97851", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "BPBul27_251.pdf", "filesize": [{"value": "83.0 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 83000.0, "url": {"label": "BPBul27_251.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/23172/files/BPBul27_251.pdf"}, "version_id": "dd27602f-fca9-43cb-b751-4311def3969b"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Phyllanthus emblica", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Euphorbiaceae", "subitem_subject_scheme": "Other"}, {"subitem_subject": "antiproliferative activity", "subitem_subject_scheme": "Other"}, {"subitem_subject": "MK-1 cell", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HeLa cell", "subitem_subject_scheme": "Other"}, {"subitem_subject": "B16F10 cell", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Antiproliferative Activity of the Main Constituents from Phyllanthus emblica", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Antiproliferative Activity of the Main Constituents from Phyllanthus emblica"}]}, "item_type_id": "2", "owner": "2", "path": ["74"], "permalink_uri": "http://hdl.handle.net/10069/8387", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-10-12"}, "publish_date": "2007-10-12", "publish_status": "0", "recid": "23172", "relation": {}, "relation_version_is_last": true, "title": ["Antiproliferative Activity of the Main Constituents from Phyllanthus emblica"], "weko_shared_id": -1}
Antiproliferative Activity of the Main Constituents from Phyllanthus emblica
http://hdl.handle.net/10069/8387
http://hdl.handle.net/10069/83872ee68d57-3c29-456b-b112-6f9fe83c9c37
名前 / ファイル | ライセンス | アクション |
---|---|---|
BPBul27_251.pdf (83.0 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2007-10-12 | |||||
タイトル | ||||||
タイトル | Antiproliferative Activity of the Main Constituents from Phyllanthus emblica | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Phyllanthus emblica | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Euphorbiaceae | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | antiproliferative activity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | MK-1 cell | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HeLa cell | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | B16F10 cell | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Zhang, Ying-Jun
× Zhang, Ying-Jun× Nagao, Tsuneatsu× Tanaka, Takashi× Yang, Chong-Ren× Okabe, Hikaru× Kouno, Isao |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Eighteen main compounds, including four norsesquiterpenoids (1?4) and 14 phenolic compounds (5?18) isolated previously from Phyllanthus emblica, together with a main constituent, proanthocyanidin polymers (19) identified at this time from the roots, were estimated for their antiproliferative activities against MK-1 (human gastric adenocarcinoma), HeLa (human uterine carcinoma), and B16F10 (murine melanoma) cells using an MTT method. All of the phenolic compounds including the major components 5?8 from the fruit juice, 8, 9, and 12 from the branches and leaves, and 19 from the roots showed stronger inhibition against B16F10 cell growth than against HeLa and MK-1 cell growth. Norsesquiterpenoid glycosides 3 and 4 from the roots exhibited significant antiproliferative activities, although their aglycon 1 and monoglucoside 2 showed no inhibitory activity against these tumor cells. | |||||
書誌情報 |
Biological & Pharmaceutical Bulletin 巻 27, 号 2, p. 251-255, 発行日 2004-02 |
|||||
出版者 | ||||||
出版者 | Pharmaceutical Society of Japan | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09186158 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1347-5215 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA10885497 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 14758047 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/bpb.27.251 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://dx.doi.org/10.1248/bpb.27.251 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Biological & Pharmaceutical Bulletin v.27(2) p.251-255, 2004 |