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Association of Tannins and Related Polyphenols with the Cyclic Peptide Gramicidin S
http://hdl.handle.net/10069/8407
http://hdl.handle.net/10069/84071c9ec89f-ef3c-471e-ab06-bd6f64933fc1
名前 / ファイル | ライセンス | アクション |
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CPBul50_258.pdf (78.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-10-12 | |||||
タイトル | ||||||
タイトル | Association of Tannins and Related Polyphenols with the Cyclic Peptide Gramicidin S | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | polyphenol | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β-turn | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hydrophobic | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | tannin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | peptide | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | epigallocatechin 3-O-gallate | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Zhang, Ying-Jun
× Zhang, Ying-Jun× Tanaka, Takashi× Betsumiya, Yayoi× Kusano, Rie× Matsuo, Atsushi× Ueda, Toshihisa× Kouno, Isao |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The association of 10 different tannins and related polyphenols with gramicidin S, a cyclic peptide having a rigid β-turn structure, has been examined using 1H-NMR spectroscopy. In the presence of pentagalloylglucose and epigallocatechin-3-O-gallate, the proton signals due to proline and the adjacent phenylalanine moieties selectively shifted to up field, suggesting a regioselective association with the β-turn structure. The association was also supported by the observation of intermolecular nuclear Overhauser effects between epigallocatechin-3-O-gallate and the peptide. In contrast, ellagitannins, biogenetically derived from pentagalloylglucose, showed small and non-selective chemical shift changes, suggesting that interaction with these tannins is relatively weak. The hydrophobicity of the tannin molecules and the steric hindrance of the interaction site are thought to be important in the association. | |||||
書誌情報 |
Chemical & Pharmaceutical Bulletin 巻 50, 号 2, p. 258-262, 発行日 2002-02 |
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出版者 | ||||||
出版者 | Pharmaceutical Society of Japan | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00092363 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1347-5223 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00602100 | |||||
PubMed番号 | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | PMID | |||||
関連識別子 | 11848219 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1248/cpb.50.258 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://dx.doi.org/10.1248/cpb.50.258 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Chemical & Pharmaceutical Bulletin v.50(2) p.258-262, 2002 |