WEKO3
アイテム
{"_buckets": {"deposit": "1d10fbf0-a26b-4905-895c-2a7c7e0673dd"}, "_deposit": {"created_by": 2, "id": "23365", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "23365"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00023365", "sets": ["74"]}, "author_link": ["98761", "98763", "98760", "98762"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "1994-11", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "11", "bibliographicPageEnd": "870", "bibliographicPageStart": "867", "bibliographicVolumeNumber": "46", "bibliographic_titles": [{"bibliographic_title": "Journal of Pharmacy and Pharmacology"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Absorption of organic anions (phenol red, bromphenol blue and bromosulphonphthalein) has been studied after their application to rat liver surface in-vivo, employing a cylindrical glass cell (i.d. 9 mm, area 0.64 cm2). Every drug appeared gradually in the blood with the peak level at about 1 h, after which its concentration declined slowly. Absorbed model drug was efficiently excreted into the bile. These observations appear to indicate the possibility of drug absorption from liver surface membrane. Absorption ratios of model drugs were estimated to be more than 59 % in 6 h. As to phenol red, its biliary recovery and metabolism ratio did not change as compared with that of i.v. administration.", "subitem_description_type": "Abstract"}]}, "item_2_description_5": {"attribute_name": "内容記述", "attribute_value_mlt": [{"subitem_description": "without figures", "subitem_description_type": "Other"}, {"subitem_description": "グラフなし", "subitem_description_type": "Other"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Journal of Pharmacy and Pharmacology, 46 (11), 867-870, 1994", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Pharmaceutical Press"}]}, "item_2_relation_11": {"attribute_name": "PubMed番号", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "7897589", "subitem_relation_type_select": "PMID"}}]}, "item_2_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00704643", "subitem_source_identifier_type": "NCID"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00223573", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Nishida, Koyo"}], "nameIdentifiers": [{"nameIdentifier": "98760", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Norihito"}], "nameIdentifiers": [{"nameIdentifier": "98761", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sasaki, Hitoshi"}], "nameIdentifiers": [{"nameIdentifier": "98762", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamura, Junzo"}], "nameIdentifiers": [{"nameIdentifier": "98763", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-24"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "JPP46_867.pdf", "filesize": [{"value": "57.8 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 57800.0, "url": {"label": "JPP46_867.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/23365/files/JPP46_867.pdf"}, "version_id": "4e0f500b-f343-471c-a3ea-3fe4c4396133"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Absorption of organic anions as model drugs following application to rat liver surface in-vivo", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Absorption of organic anions as model drugs following application to rat liver surface in-vivo"}]}, "item_type_id": "2", "owner": "2", "path": ["74"], "permalink_uri": "http://hdl.handle.net/10069/6671", "pubdate": {"attribute_name": "公開日", "attribute_value": "2007-02-21"}, "publish_date": "2007-02-21", "publish_status": "0", "recid": "23365", "relation": {}, "relation_version_is_last": true, "title": ["Absorption of organic anions as model drugs following application to rat liver surface in-vivo"], "weko_shared_id": -1}
Absorption of organic anions as model drugs following application to rat liver surface in-vivo
http://hdl.handle.net/10069/6671
http://hdl.handle.net/10069/66713303483d-a5a7-44bc-8328-084de622ccd6
名前 / ファイル | ライセンス | アクション |
---|---|---|
JPP46_867.pdf (57.8 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2007-02-21 | |||||
タイトル | ||||||
タイトル | Absorption of organic anions as model drugs following application to rat liver surface in-vivo | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Nishida, Koyo
× Nishida, Koyo× Sato, Norihito× Sasaki, Hitoshi× Nakamura, Junzo |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Absorption of organic anions (phenol red, bromphenol blue and bromosulphonphthalein) has been studied after their application to rat liver surface in-vivo, employing a cylindrical glass cell (i.d. 9 mm, area 0.64 cm2). Every drug appeared gradually in the blood with the peak level at about 1 h, after which its concentration declined slowly. Absorbed model drug was efficiently excreted into the bile. These observations appear to indicate the possibility of drug absorption from liver surface membrane. Absorption ratios of model drugs were estimated to be more than 59 % in 6 h. As to phenol red, its biliary recovery and metabolism ratio did not change as compared with that of i.v. administration. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | without figures | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | グラフなし | |||||
書誌情報 |
Journal of Pharmacy and Pharmacology 巻 46, 号 11, p. 867-870, 発行日 1994-11 |
|||||
出版者 | ||||||
出版者 | Pharmaceutical Press | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00223573 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00704643 | |||||
PubMed番号 | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | PMID | |||||
関連識別子 | 7897589 | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Pharmacy and Pharmacology, 46 (11), 867-870, 1994 |