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Evaluation of Effectiveness of Chemotherapy in Cholera
http://hdl.handle.net/10069/4088
http://hdl.handle.net/10069/4088aa3fd54d-bc4e-43a9-8b3c-9a59623d0564
名前 / ファイル | ライセンス | アクション |
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tm13_01_04_t.pdf (1.5 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-04-26 | |||||
タイトル | ||||||
タイトル | Evaluation of Effectiveness of Chemotherapy in Cholera | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Nakatomi, Masao
× Nakatomi, Masao |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Chloramphenicol has recently been criticised as antibacterial drug for cholera because of probable inactivation in the body and appearance of resistant strains of Vibrio cholerae. In the present study, chloramphenicol was compared with dihydroxymethyl furalazine in regard to amount of diarrhea, reduction of vibrios in stool and the drug concentration in stool and blood. 1. With oral administration of chloramphenicol, neither reduction of vibrios nor elevation of drug level in stool were seen. 2. Two cases with intravenous administration of chloramphenicol revealed high concentration of the drug and marked reduce of vibrios in stool. 3. In all cases with oral administration of furalazine, effective concentration of the drug in stool was regularly found and at the same time, remarkable decrease of the number of vibrios was recognized. Moreover, it was observed that vibrios disappeared in stool in almost all cases, as the level of the drug showed further elevation. 4. An untoward reaction of furalazine, vomiting, was seen in one case. Furalazine can be recommended as a substitutional drug for treatment of cholera. | |||||
書誌情報 |
熱帯医学 Tropical medicine 巻 13, 号 1, p. 26-43, 発行日 1971-03-15 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03855643 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00199644 | |||||
出版者 | ||||||
出版者 | 長崎大学熱帯医学研究所 | |||||
出版者別言語 | ||||||
Institute of Tropical Medicine, Nagasaki University | ||||||
sortkey | ||||||
P00026-P00043 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 熱帯医学 Tropical medicine 13(1). p26-43, 1971 |