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鉄負荷によるラット実験肝癌の抑制
http://hdl.handle.net/10069/4285
http://hdl.handle.net/10069/4285388bc9bc-fc93-4cdf-9824-5e07b3abaad9
名前 / ファイル | ライセンス | アクション |
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tm22_03_04_t.pdf (1.5 MB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-04-26 | |||||
タイトル | ||||||
タイトル | 鉄負荷によるラット実験肝癌の抑制 | |||||
言語 | ||||||
言語 | jpn | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
山下, 裕人
× 山下, 裕人× 飯田, 芙佐枝× 石井, 三和子× 千馬, 正敬× 板倉, 英世 |
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著者別名 | ||||||
姓名 | Yamashita, Hiroto | |||||
著者別名 | ||||||
姓名 | Iida, Fusae | |||||
著者別名 | ||||||
姓名 | Ishii, Miwako | |||||
著者別名 | ||||||
姓名 | Senba, Masachika | |||||
著者別名 | ||||||
姓名 | Itakura, Hideyo | |||||
その他のタイトル | ||||||
その他のタイトル | The Inhibitory Effect of Iron-overload on the Chemically-induced Hepatocarcinogenesis in Rats. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Effects of iron-overload on the chemically-induced carcinogenesis of the rat liver were studied. The rats were given 2% of ferric amonium citrate in drinking water for 3 weeks, usual drinking water for 1 week and then 50 ppm diethylnitrosamine. The rats of the control group were given usual drinking water for 4 weeks and then 50 ppm diethylnitrosamine. Each paired group composed of treated rats and control rats given diethylnitrosamine for the same period was sacrificed simultaneously at the different experimental periods. The hepatoma nodules and the size of each nodule were examined. Then the histopathological study of the liver was done. The comparison of the development of the hepatoma, estimated by the number and sizes of the nodules, were made in each paired group. Although 16 paired groups were tested, the comparison could be made only in 10 pairs. Nine pairs showed more developed hepatoma nodules in the control group than in the treated group and one pair showed the reversed result. Sign test was done and the calculated probability of the observed result was 0.0107. This result suggests that ironoverload inhibits the carcinogenicity of diethylnitrosamine in rats. | |||||
書誌情報 |
熱帯医学 Tropical medicine 巻 22, 号 3, p. 173-180, 発行日 1980-10-30 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03855643 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00199644 | |||||
出版者 | ||||||
出版者 | 長崎大学熱帯医学研究所 | |||||
出版者別言語 | ||||||
Institute of Tropical Medicine, Nagasaki University | ||||||
sortkey | ||||||
P00173-P00180 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 熱帯医学 Tropical medicine 22(3). p173-180, 1980 |