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スナネズミに感染させたBrugia pahangiの仔虫に対するジエチルカルバマジンの治療効果
http://hdl.handle.net/10069/4355
http://hdl.handle.net/10069/435525f91a7e-e6ba-47fd-a65e-ce17e9bc9c34
名前 / ファイル | ライセンス | アクション |
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tm25_03_01_t.pdf (450.8 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-04-26 | |||||
タイトル | ||||||
タイトル | スナネズミに感染させたBrugia pahangiの仔虫に対するジエチルカルバマジンの治療効果 | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
山下, 征二
× 山下, 征二× 重野, 鎮義× 木村, 英作× 青木, 克己 |
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著者別名 | ||||||
姓名 | Yamashita, Seiji | |||||
著者別名 | ||||||
姓名 | Shigeno, Shizugi | |||||
著者別名 | ||||||
姓名 | Kimura, Eisaku | |||||
著者別名 | ||||||
姓名 | Aoki, Yoshiki | |||||
その他のタイトル | ||||||
その他のタイトル | The Effect of Diethylcarbamazine on Microfilariae of Brugia pahangi in Mongolian Jirds (Meriones unguiculatus) | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | ジエチルカルバマジン(DEC)を,スナネズミ体重1kg当り300mg宛,腹腔内に1日1回,5日間連続投与した場合,或は,同量のDECを43日間にわたり2日おきに15回投与した場合,スナネズミ血液中のB. pahangi仔虫数に明らかな減少を認めた. DECの15回投与は,5回投与に比し,その効果はより強く持続的で,薬量依存の傾向がみられた.胃内挿管法によりDEC 300mg/kgを8回投与した場合の治療効果は,前2者に比べて劣ることが観察された. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Diethylcarbamazine (DEC) was effective in reducing microfilarial densities of Brugia pahangi in Mongolian jirds (Meriones unguiculatus) when it was administered intraperitoneally at the daily dosage of 300 mg/kg of body weight either for 5 consecutive days or every 3 days for 43 days with the total of 15 doses. The latter treatment scheme seemed to be more effective than the former, suggesting that the effect was dose-dependent. The DEC treatment by stomach intubation seemed to be less effective than the intraperitoneal administration of the medicine. | |||||
書誌情報 |
熱帯医学 Tropical medicine 巻 25, 号 3, p. 113-117, 発行日 1983-09-30 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03855643 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00199644 | |||||
出版者 | ||||||
出版者 | 長崎大学熱帯医学研究所 | |||||
出版者別言語 | ||||||
Institute of Tropical Medicine, Nagasaki University | ||||||
sortkey | ||||||
P00113-P00117 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 熱帯医学 Tropical medicine 25(3). p113-117, 1983 |