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アイテム
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沖繩における糞線虫感染と成人T細胞白血病ウイルス感染との関連についての血清疫学的研究
http://hdl.handle.net/10069/4421
http://hdl.handle.net/10069/44217517d11a-1750-455b-afe0-072aa42ecf83
名前 / ファイル | ライセンス | アクション |
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tm27_04_03_t.pdf (588.2 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2006-04-26 | |||||
タイトル | ||||||
タイトル | 沖繩における糞線虫感染と成人T細胞白血病ウイルス感染との関連についての血清疫学的研究 | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
藤田, 紘一郎
× 藤田, 紘一郎× 月舘, 説子× 田島, 和雄× 富永, 祐民× 仲田, 精伸× 今井, 浄子× 日沼, 頼夫 |
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著者別名 | ||||||
姓名 | Fujita, Koichiro | |||||
著者別名 | ||||||
姓名 | Tsukidate, Setsuko | |||||
著者別名 | ||||||
姓名 | Tajima, Kazuo | |||||
著者別名 | ||||||
姓名 | Tominaga, Suketami | |||||
著者別名 | ||||||
姓名 | Nakada, Kiyonobu | |||||
著者別名 | ||||||
姓名 | Imai, Junko | |||||
著者別名 | ||||||
姓名 | Hinuma, Yorio | |||||
その他のタイトル | ||||||
その他のタイトル | Seroepidemiological Studies of Strongyloides Infection in Adult T-cell Leukemia Virus Carriers in Okinawa Island, Japan | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | 糞線虫感染者の間には,高率に成人T細胞白血病ウイルス(ATLV)抗体陽性者が見出されることを我々は先に報告した.今回,我々は,沖繩協同病院を中心とした沖繩本島の糞線虫患者,29才から91才までの64例を選び,対照者として糞線虫感染がみられない同地区住民127名を選んで,ATLV感染におよぼす糞線虫感染の影響を血清疫学的手法を用いて研究した.すなわち,彼らの血清についてATLV抗体価と糞線虫抗体価を測定し,あわせて,T細胞機能としてEBウイルス核抗原に対する抗体(EBNA)とEBウイルス・カプシッドIgG抗体(VCA)を間接螢光抗体法で測定し,対照群と相互に比較した.糞線虫感染者のATLV抗体陽性率は57.8%であった.一方,対照群の陽性率は20.5%で,糞線虫感染者がはるかに高いATLV抗体陽性率を示した.糞線虫感染者のうち,ATLV抗体陽性者群の糞線虫抗体価は,陰性者群の抗体価に比べ,有意に低下していた.またEBNA抗体価も有意ではないが低下していた.すなわち,糞線虫感染者のうち,ATLV抗体陽性者群の血清抗体価およびT細胞機能が低下傾向にあることが観察された. | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Patients with Strongyloides stercoralis are commonly observed in Okinawa, the most southern prefecture in Japan, where adult T-cell leukemia/lymphoma (ATLL) is endemic. More than half (58%) of strongyloides-carriers, whereas only 21% of parasitefree adults had positive antibody to adult T-cell leukemia virus (ATLV) associated antigen (ATLA). A mean titer of antibody to strongyloides-antigen in 37 ATLV-carriers was significantly (p<0.05) lower than that in 27 non-carriers among strongyloides-carriers. However, there was no difference in the distributions of antibody titers against Epstein-Barr virus-specific antigens between them. These results suggest that some individuals, especially among ATLV-carriers, might have subclinical immunodeficiency, which may cause a low humoral response to strongyloides antigen and may lead to persistent infection with Strongyloides stercoralis. | |||||
書誌情報 |
熱帯医学 Tropical medicine 巻 27, 号 4, p. 203-209, 発行日 1985-12-28 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 03855643 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AN00199644 | |||||
出版者 | ||||||
出版者 | 長崎大学熱帯医学研究所 | |||||
出版者別言語 | ||||||
Institute of Tropical Medicine, Nagasaki University | ||||||
sortkey | ||||||
P00203-P00209 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 熱帯医学 Tropical medicine 27(4). p203-209, 1985 |