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Relationship between serum ghrelin level and physiology in patients who underwent hepatectomy and pancreatectomy
http://hdl.handle.net/10069/37731
http://hdl.handle.net/10069/37731f9e7bde1-4e13-4e84-9264-08e114ef8bba
名前 / ファイル | ライセンス | アクション |
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ActMed61_55.pdf (601.9 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2017-08-18 | |||||
タイトル | ||||||
タイトル | Relationship between serum ghrelin level and physiology in patients who underwent hepatectomy and pancreatectomy | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | human ghrelin level | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | postoperative nutrition | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatectomy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | pancreatectomy | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Nanashima, Atsushi
× Nanashima, Atsushi× Murakami, Goushi× Takagi, Katsunori× Arai, Junichi× Sumida, Yorihisa× Kodama, Tomoaki× Nagayasu, Takeshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Aim: Ghrelin is a peptide that is secreted from the stomach and plays a role in appetite, weight gain, and skeletal muscle composition. In the present clinical study, we examined the relationship between ghrelin level and physiology in patients who had undergone major liver and pancreas surgery. Methods: Serum ghrelin level was measured before and after hepatectomy and pancreatectomy. The relationships between nutritional status and postoperative alterations of parameters including the ghrelin level were examined. Results: In 32 patients, the preoperative plasm acyl- (AG) or des-acyl-ghrelin (DAG) and AG/DAG ratio were not significantly different based on gender, type of operation, age and each disease. AG tended to be correlated with the respiration quotient but this was not statistically significant (p=0.08). AG was significantly negatively correlated with hemoglobin and albumin levels. The postoperative plasma ghrelin level was significantly decreased at day 1 in comparison with preoperative levels (p<0.05) and recovered to preoperative levels at day 3. There were no significant differences between hepatectomy and pancreatectomy groups, with no changes of postoperative metabolic parameters. Conclusions: Although serum ghrelin level was transiently decreased, this level was immediately recovered and not influenced by the surgical procedures or its invasiveness. |
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書誌情報 |
Acta medica Nagasakiensia 巻 61, 号 2, p. 55-60, 発行日 2017-08 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
長崎大学医学部 | ||||||
sortkey | ||||||
02 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia, 61(2), pp.55-60; 2017 |