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PREBIOTIC EFFECT OF DAILY FRUCTOOLIGOSACCHARIDE INTAKE ON WEIGHT GAIN AND REDUCTION OF ACUTE DIARRHEA AMONG CHILDREN IN A BANGLADESH URBAN SLUM: A Randomized Double-masked Placebo-controlled Study
http://hdl.handle.net/10069/5668
http://hdl.handle.net/10069/56681fa59d53-4d77-4c62-9706-7d70f40e1ae0
名前 / ファイル | ライセンス | アクション |
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TMH34_03_125.pdf (55.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2007-02-08 | |||||
タイトル | ||||||
タイトル | PREBIOTIC EFFECT OF DAILY FRUCTOOLIGOSACCHARIDE INTAKE ON WEIGHT GAIN AND REDUCTION OF ACUTE DIARRHEA AMONG CHILDREN IN A BANGLADESH URBAN SLUM: A Randomized Double-masked Placebo-controlled Study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | prebiotic effect | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | fructooligosaccharide (FOS) | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | weight gain | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | diarrhea | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | RCT | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Nakamura, Sadako
× Nakamura, Sadako× Shafiqul, Alam Sarker× Mohammad, Abdul Wahed× Wagatsuma, Yukiko× Oku, Tsuneyuki× Moji, Kazuhiko |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Fructooligosaccharide (FOS) is a typical prebiotic agent. A randomized, double-masked, placebo-controlled study was performed to evaluate the prebiotic effect of daily intake of an isotonic solution containing FOS on body weight gain and the reduction of diarrhea in children in an urban slum in Bangladesh over six consecutive months. We enrolled a total of 150 children, aged 25-59 months. Sixty-four children in the FOS group received 50 mL of isotonic solution with 2 g of FOS added, and 69 children in the placebo group were given an identical solution with 1 g of glucose added, once a day. The measurement of body weight was carried out every other day; height and arm circumference were measured once a month; and the children‘s mothers were interviewed to obtain data about diarrhea, the consistency and constitution of stool, other symptoms, and antibiotic treatment. As a result, the body weight gain during the six-month period was 0.86±0.55 kg in the FOS group and 0.89±0.48 kg in the placebo group, while the increase in height and arm circumference were not significantly different between the two groups. The number of diarrhea episodes during the six-month period was not significantly different. A significant reduction in the duration of diarrhea days and of duration per episode was observed in the FOS group (p=0.039 and p=0.008, respectively). In conclusion, daily intake of FOS was associated neither with the children‘s growth nor with the number of diarrhea episodes, but a significant reduction in the duration of diarrhea days was observed. Further studies are needed to confirm the effects of FOS by changing the doses and eliminating the influence of antibiotics. | |||||
書誌情報 |
Tropical medicine and health 巻 34, 号 3, p. 125-131, 発行日 2006-10 |
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出版者 | ||||||
出版者 | 日本熱帯医学会 | |||||
出版者別言語 | ||||||
The Japanese Society of Tropical Medicine | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13488945 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1349-4147 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA11912846 | |||||
権利 | ||||||
権利情報 | Copyright© 2006 by The Japanese Society of Tropical Medicine | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
関係URI | ||||||
関連名称 | http://www.jstage.jst.go.jp/article/tmh/34/3/125/_pdf/-char/ja/ | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Tropical Medicine and Health Vol. 34 No. 3, 2006, pp. 125-131 |