WEKO3
アイテム
{"_buckets": {"deposit": "edc3bdb8-e21f-4757-87d8-e31f07ccc53d"}, "_deposit": {"created_by": 2, "id": "2683", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "2683"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00002683", "sets": ["9"]}, "author_link": ["12306", "12309", "12308", "12311", "12307", "12312", "12310"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2018-01", "bibliographicIssueDateType": "Issued"}, "bibliographicPageEnd": "186", "bibliographicPageStart": "179", "bibliographicVolumeNumber": "106", "bibliographic_titles": [{"bibliographic_title": "Bone"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "The effects of zoledronic acid on hip structural and biomechanical properties were evaluated in Japanese patients with osteoporosis by computed tomography (CT). The subjects included in this study were a subset of female subjects (zoledronic acid group, 49 subjects; placebo group, 53 subjects) in the phase 3 trial (ZONE study) who were available for multi-detector row CT (MDCT) scanning. Eligible subjects were those diagnosed with primary osteoporosis based on the Diagnostic Criteria for Primary Osteoporosis (2000) by the Japanese Society for Bone and Mineral Research and who had between one and four fractured vertebrae located between the fourth thoracic vertebra and the fourth lumbar vertebra. The subjects received a once-yearly intravenous infusion of zoledronic acid 5 mg or placebo for two years. CT data were obtained at baseline and at 12 and 24 months later and analyzed under blinded conditions. The results demonstrated that once-yearly intravenous infusion of zoledronic acid improved volumetric bone mineral density (vBMD), cortical bone geometry parameters, and CT-derived biomechanical parameters at the femoral neck, intertrochanteric region, and shaft; particularly at the intertrochanteric region, significant improvements in cortical bone geometry parameters and CT-derived biomechanical parameters, compared with those in the placebo group, were detectable early, at 12 months. The present data suggest that zoledronic acid has a possibility to reduce the risk of hip fractures in Japanese patients with osteoporosis.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Bone, 106, pp.179-186; 2018", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier Inc."}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.bone.2017.10.013", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/)."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "87563282", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Ito, Masako"}], "nameIdentifiers": [{"nameIdentifier": "12306", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sone, Teruki"}], "nameIdentifiers": [{"nameIdentifier": "12307", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shiraki, Masataka"}], "nameIdentifiers": [{"nameIdentifier": "12308", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tanaka, Satoshi"}], "nameIdentifiers": [{"nameIdentifier": "12309", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Irie, Chika"}], "nameIdentifiers": [{"nameIdentifier": "12310", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ota, Yuri"}], "nameIdentifiers": [{"nameIdentifier": "12311", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamura, Toshitaka"}], "nameIdentifiers": [{"nameIdentifier": "12312", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "Bone106_179.pdf", "filesize": [{"value": "1.1 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1100000.0, "url": {"label": "Bone106_179.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/2683/files/Bone106_179.pdf"}, "version_id": "e22ad80c-607b-458a-b69d-d5f12f85587a"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Bisphosphonate", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Zoledronic acid", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Hip geometry", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Bone mineral density", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Computed tomography", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Biomechanical property", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "The effect of once-yearly zoledronic acid on hip structural and biomechanical properties derived using computed tomography (CT) in Japanese women with osteoporosis", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "The effect of once-yearly zoledronic acid on hip structural and biomechanical properties derived using computed tomography (CT) in Japanese women with osteoporosis"}]}, "item_type_id": "2", "owner": "2", "path": ["9"], "permalink_uri": "http://hdl.handle.net/10069/37905", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-11-28"}, "publish_date": "2017-11-28", "publish_status": "0", "recid": "2683", "relation": {}, "relation_version_is_last": true, "title": ["The effect of once-yearly zoledronic acid on hip structural and biomechanical properties derived using computed tomography (CT) in Japanese women with osteoporosis"], "weko_shared_id": -1}
The effect of once-yearly zoledronic acid on hip structural and biomechanical properties derived using computed tomography (CT) in Japanese women with osteoporosis
http://hdl.handle.net/10069/37905
http://hdl.handle.net/10069/37905fc85f0cc-7ed0-4fe0-bcfc-47e456db5059
名前 / ファイル | ライセンス | アクション |
---|---|---|
Bone106_179.pdf (1.1 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-11-28 | |||||
タイトル | ||||||
タイトル | The effect of once-yearly zoledronic acid on hip structural and biomechanical properties derived using computed tomography (CT) in Japanese women with osteoporosis | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bisphosphonate | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Zoledronic acid | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hip geometry | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bone mineral density | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Computed tomography | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Biomechanical property | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ito, Masako
× Ito, Masako× Sone, Teruki× Shiraki, Masataka× Tanaka, Satoshi× Irie, Chika× Ota, Yuri× Nakamura, Toshitaka |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | The effects of zoledronic acid on hip structural and biomechanical properties were evaluated in Japanese patients with osteoporosis by computed tomography (CT). The subjects included in this study were a subset of female subjects (zoledronic acid group, 49 subjects; placebo group, 53 subjects) in the phase 3 trial (ZONE study) who were available for multi-detector row CT (MDCT) scanning. Eligible subjects were those diagnosed with primary osteoporosis based on the Diagnostic Criteria for Primary Osteoporosis (2000) by the Japanese Society for Bone and Mineral Research and who had between one and four fractured vertebrae located between the fourth thoracic vertebra and the fourth lumbar vertebra. The subjects received a once-yearly intravenous infusion of zoledronic acid 5 mg or placebo for two years. CT data were obtained at baseline and at 12 and 24 months later and analyzed under blinded conditions. The results demonstrated that once-yearly intravenous infusion of zoledronic acid improved volumetric bone mineral density (vBMD), cortical bone geometry parameters, and CT-derived biomechanical parameters at the femoral neck, intertrochanteric region, and shaft; particularly at the intertrochanteric region, significant improvements in cortical bone geometry parameters and CT-derived biomechanical parameters, compared with those in the placebo group, were detectable early, at 12 months. The present data suggest that zoledronic acid has a possibility to reduce the risk of hip fractures in Japanese patients with osteoporosis. | |||||
書誌情報 |
Bone 巻 106, p. 179-186, 発行日 2018-01 |
|||||
出版者 | ||||||
出版者 | Elsevier Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 87563282 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.bone.2017.10.013 | |||||
権利 | ||||||
権利情報 | c 2017 The Authors. Published by Elsevier Inc. This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Bone, 106, pp.179-186; 2018 |