WEKO3
アイテム
{"_buckets": {"deposit": "9e072085-9283-4da2-bffc-f6082bf5f4bb"}, "_deposit": {"created_by": 6, "id": "27114", "owners": [6], "pid": {"revision_id": 0, "type": "depid", "value": "27114"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00027114", "sets": ["2019"]}, "author_link": ["120818", "120813", "120814", "120812", "120817", "120816", "120811", "120815"], "item_3_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2022-01", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "36", "bibliographicPageStart": "29", "bibliographicVolumeNumber": "65", "bibliographic_titles": [{"bibliographic_title": "Acta medica Nagasakiensia"}]}]}, "item_3_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Purpose: Olfactory deficit has been studied in aging, amnestic mild cognitive impairment (aMCI), Alzheimer’s disease (AD). Parkinson\u0027s disease (PD), dementia with Lewy bodies (DLB) and idiopathic REM-sleep behavior disorder (iRBD). Our aim was to investigate the usefulness of a simple test kit “The Odor Stick Identification test for the Japanese ”(OSIT-J) in clinical practice.\nMethods: A total of 240 patients were enrolled in this study, including 44 cognitively normal subjects (NS), 31 patients with aMCI, 70 patients with mild AD (AD-mild), 28 patients with DLB, 31 patients with PD and 36 patients with iRBD. The OSIT-J consists of 12 types of odor sticks. The subjects were asked to select an odor from a list of 4 odors that were rubbed on the medicine wraping paper for each odor stick. The maximum score was 12.\nResults: The mean odor identification (OI) score decreased in the order of aMCI, iRBD, AD-mild, PD and DLB (NS: aMCI, P\u003c0.05, NS: AD-mild, DLB, PD and iRBD, P\u003c0.001, aMCI: DLB, P\u003c0.001, aMCI: PD, P\u003c0.01 (Kruskal-Wallis, Dunn’s test). The sensitivity and specificity in differentiating each disease from NS at a cutoff value of 8 was 96.8% and 79.5%, respectively, in PD, and 96.4% and 79.5% in DLB. An ageing effect was observed in NSs ( r=-0.453 (p\u003c0.01)).\nConclusions: Olfactory deficit is a non-specific phenomenon. However, it is important to be aware of the underlying diseases or future development of diseases. The OSIT-J, which is a simple test, is useful for detecting OI abnormalities in daily clinical practice.", "subitem_description_type": "Abstract"}]}, "item_3_description_64": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Acta medica Nagasakiensia, 65(2), pp.29-36; 2022", "subitem_description_type": "Other"}]}, "item_3_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Nagasaki University School of Medicine"}]}, "item_3_source_id_10": {"attribute_name": "書誌レコードID", "attribute_value_mlt": [{"subitem_source_identifier": "AA00508430", "subitem_source_identifier_type": "NCID"}]}, "item_3_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00016055", "subitem_source_identifier_type": "ISSN"}]}, "item_3_text_62": {"attribute_name": "sortkey", "attribute_value_mlt": [{"subitem_text_value": "01"}]}, "item_3_text_63": {"attribute_name": "出版者別言語", "attribute_value_mlt": [{"subitem_text_value": "長崎大学医学部"}]}, "item_3_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Yokogi, Maiko"}], "nameIdentifiers": [{"nameIdentifier": "120811", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kusano, Kayoko"}], "nameIdentifiers": [{"nameIdentifier": "120812", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Matsubara, Rie"}], "nameIdentifiers": [{"nameIdentifier": "120813", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sato, Maki"}], "nameIdentifiers": [{"nameIdentifier": "120814", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tomita, Itsuro"}], "nameIdentifiers": [{"nameIdentifier": "120815", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Seto, Makiko"}], "nameIdentifiers": [{"nameIdentifier": "120816", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Satoh, Akira"}], "nameIdentifiers": [{"nameIdentifier": "120817", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tsujihata, Mitsuhiro"}], "nameIdentifiers": [{"nameIdentifier": "120818", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2022-02-25"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "ActMed65_29.pdf", "filesize": [{"value": "672.9 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 672900.0, "url": {"label": "ActMed65_29.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/27114/files/ActMed65_29.pdf"}, "version_id": "0e5f01a6-e18e-40d4-a3ad-cd4a6910b616"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Odor identification", "subitem_subject_scheme": "Other"}, {"subitem_subject": "OSIT-J", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Alzheimer\u0027s disease", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Dementia with Lewy bodies", "subitem_subject_scheme": "Other"}, {"subitem_subject": "amnestic mild cognitive impairment", "subitem_subject_scheme": "Other"}, {"subitem_subject": "REM sleep behavior disorder", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Parkinson\u0027s disease", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "departmental bulletin paper", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases"}]}, "item_type_id": "3", "owner": "6", "path": ["2019"], "permalink_uri": "http://hdl.handle.net/10069/00041275", "pubdate": {"attribute_name": "公開日", "attribute_value": "2022-02-25"}, "publish_date": "2022-02-25", "publish_status": "0", "recid": "27114", "relation": {}, "relation_version_is_last": true, "title": ["Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases"], "weko_shared_id": -1}
Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases
http://hdl.handle.net/10069/00041275
http://hdl.handle.net/10069/000412750c306a94-9246-40a3-ad38-4e942bc60bdf
名前 / ファイル | ライセンス | アクション |
---|---|---|
ActMed65_29.pdf (672.9 kB)
|
|
Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2022-02-25 | |||||
タイトル | ||||||
タイトル | Evaluation of olfactory impairment using a simple test kit “The Odor Stick Identification test for the Japanese” (OSIT-J) in neurodegenerative diseases | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Odor identification | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | OSIT-J | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Alzheimer's disease | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Dementia with Lewy bodies | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | amnestic mild cognitive impairment | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | REM sleep behavior disorder | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Parkinson's disease | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Yokogi, Maiko
× Yokogi, Maiko× Kusano, Kayoko× Matsubara, Rie× Sato, Maki× Tomita, Itsuro× Seto, Makiko× Satoh, Akira× Tsujihata, Mitsuhiro |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose: Olfactory deficit has been studied in aging, amnestic mild cognitive impairment (aMCI), Alzheimer’s disease (AD). Parkinson's disease (PD), dementia with Lewy bodies (DLB) and idiopathic REM-sleep behavior disorder (iRBD). Our aim was to investigate the usefulness of a simple test kit “The Odor Stick Identification test for the Japanese ”(OSIT-J) in clinical practice. Methods: A total of 240 patients were enrolled in this study, including 44 cognitively normal subjects (NS), 31 patients with aMCI, 70 patients with mild AD (AD-mild), 28 patients with DLB, 31 patients with PD and 36 patients with iRBD. The OSIT-J consists of 12 types of odor sticks. The subjects were asked to select an odor from a list of 4 odors that were rubbed on the medicine wraping paper for each odor stick. The maximum score was 12. Results: The mean odor identification (OI) score decreased in the order of aMCI, iRBD, AD-mild, PD and DLB (NS: aMCI, P<0.05, NS: AD-mild, DLB, PD and iRBD, P<0.001, aMCI: DLB, P<0.001, aMCI: PD, P<0.01 (Kruskal-Wallis, Dunn’s test). The sensitivity and specificity in differentiating each disease from NS at a cutoff value of 8 was 96.8% and 79.5%, respectively, in PD, and 96.4% and 79.5% in DLB. An ageing effect was observed in NSs ( r=-0.453 (p<0.01)). Conclusions: Olfactory deficit is a non-specific phenomenon. However, it is important to be aware of the underlying diseases or future development of diseases. The OSIT-J, which is a simple test, is useful for detecting OI abnormalities in daily clinical practice. |
|||||
書誌情報 |
Acta medica Nagasakiensia 巻 65, 号 2, p. 29-36, 発行日 2022-01 |
|||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
長崎大学医学部 | ||||||
sortkey | ||||||
01 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia, 65(2), pp.29-36; 2022 |