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Effect of Hemocoagulase on the Prevention of Bleeding after Percutaneous Renal Biopsy
http://hdl.handle.net/10069/00041397
http://hdl.handle.net/10069/00041397f5c6c124-322d-4a9d-b8df-049394d4f03e
名前 / ファイル | ライセンス | アクション |
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Toxins14-223.pdf (929.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2022-04-18 | |||||
タイトル | ||||||
タイトル | Effect of Hemocoagulase on the Prevention of Bleeding after Percutaneous Renal Biopsy | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | renal biopsy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | complication | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hemocoagulase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | post-procedural bleeding | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Torigoe, Kenta
× Torigoe, Kenta× Yamashita, Ayuko× Abe, Shinichi× Muta, Kumiko× Nishino, Tomoya |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A percutaneous renal biopsy is an essential tool for the diagnosis of various renal diseases;however, post-biopsy bleeding is a major complication. Hemocoagulase is a detoxified and purified snake venom enzyme that is widely used to prevent post-procedural bleeding. In this study, we retrospectively analyzed the effect of hemocoagulase on post-renal biopsy bleeding. We included 221 patients who underwent percutaneous renal biopsy between April 2017 and December 2020 and analyzed post-renal biopsy hemoglobin (Hb) decline in patients who were administered a periprocedural hemocoagulase injection. After the renal biopsy, the mean Hb decrease in the entire patient cohort was 0.33 ・ 0.84 g/dL. Periprocedural hemocoagulase injection lowered the Hb decline post-renal biopsy (0.50 ・ 0.87 vs. 0.23 ・ 0.80 g/dL, p = 0.0204). The propensity-matched cohort was also adjusted for factors influencing postprocedural bleeding; periprocedural hemocoagulase injection reduced the Hb decline post-renal biopsy (0.56 ・ 0.89 vs. 0.17 ・ 0.74 g/dL, p = 0.006). There were no adverse events (e.g., thrombosis and anaphylactic shock) due to hemocoagulase. Our study demonstrated the beneficial effect of hemocoagulase on post-renal biopsy Hb decline, suggesting its clinical value in preventing post-renal biopsy bleeding. | |||||
書誌情報 |
Toxins 巻 14, 号 3, p. 223, 発行日 2022-03-28 |
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出版者 | ||||||
出版者 | MDPI | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/toxins14030223 | |||||
権利 | ||||||
権利情報 | ©2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https:// creativecommons.org/licenses/by/ 4.0/) | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Toxins, 14(3), art.no.223; 2022 |