WEKO3
アイテム
{"_buckets": {"deposit": "70889254-0119-41b1-a823-e7f816c37a3b"}, "_deposit": {"created_by": 6, "id": "27730", "owners": [6], "pid": {"revision_id": 0, "type": "depid", "value": "27730"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00027730", "sets": ["9"]}, "author_link": ["123357", "123363", "123364", "123360", "123362", "123359", "123365", "123356", "123358", "123361"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2022-10-06", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "10", "bibliographicPageStart": "527", "bibliographicVolumeNumber": "9", "bibliographic_titles": [{"bibliographic_title": "Bioengineering"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Previous studies have reported a close correlation between vascular endothelial growth factor (VEGF), which plays an important role in angiogenesis, and human T-cell leukemia virus 1 (HTLV-1). However, an association between genetic characteristics related to VEGF and HTLV-1 infection has not yet been reported. Because the VEGF polymorphism rs3025039 is inversely associated with serum concentrations of VEGF, we focus on rs3025039 in the present study. To clarify the association between the VEGF polymorphism rs3025039 and HTLV-1 infection, a cross-sectional study of 1924 Japanese individuals aged 60–79 years who participated in general health check-ups was conducted. Using logistic regression, odds ratios (ORs) and 95% confidence intervals (CIs) for HTLV-1 infection in relation to rs3025039 genotype were calculated with adjustment for known confounders. Compared with rs3025039 CC-homozygotes, (T) allele carriers had a significantly lower OR for HTLV-1 infection. The adjusted OR and 95% CI for HTLV-1 infection was 0.70 (0.54–0.91) (p = 0.009). Genetic characteristics related to lower angiogenesis activity might be associated with a lower chance of establishing HTLV-1 infection. Although further investigation is necessary, angiogenesis might play a crucial role in the establishment of HTLV-1 infection.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Bioengineering, 9(10), art. no. 527; 2022", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "MDPI"}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.3390/bioengineering9100527", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "© 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/)."}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "2306-5354", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_970fb48d4fbd8a85", "subitem_version_type": "VoR"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Shimizu, Yuji"}], "nameIdentifiers": [{"nameIdentifier": "123356", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Yamanashi, Hirotomo"}], "nameIdentifiers": [{"nameIdentifier": "123357", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Miyata, Jun"}], "nameIdentifiers": [{"nameIdentifier": "123358", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takada, Midori"}], "nameIdentifiers": [{"nameIdentifier": "123359", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Noguchi, Yuko"}], "nameIdentifiers": [{"nameIdentifier": "123360", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Honda, Yukiko"}], "nameIdentifiers": [{"nameIdentifier": "123361", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nonaka, Fumiaki"}], "nameIdentifiers": [{"nameIdentifier": "123362", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nakamichi, Seiko"}], "nameIdentifiers": [{"nameIdentifier": "123363", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Nagata, Yasuhiro"}], "nameIdentifiers": [{"nameIdentifier": "123364", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Maeda, Takahiro"}], "nameIdentifiers": [{"nameIdentifier": "123365", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2022-11-08"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "B9_527.pdf", "filesize": [{"value": "254.5 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 254500.0, "url": {"label": "B9_527.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/27730/files/B9_527.pdf"}, "version_id": "66839edb-cbf8-4e53-9697-587a0ba71282"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "angiogenesis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "HTLV-1", "subitem_subject_scheme": "Other"}, {"subitem_subject": "rs3025039", "subitem_subject_scheme": "Other"}, {"subitem_subject": "SNP", "subitem_subject_scheme": "Other"}, {"subitem_subject": "VEGF", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "VEGF Polymorphism rs3025039 and Human T-Cell Leukemia Virus 1 (HTLV-1) Infection among Older Japanese Individuals: A Cross-Sectional Study", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "VEGF Polymorphism rs3025039 and Human T-Cell Leukemia Virus 1 (HTLV-1) Infection among Older Japanese Individuals: A Cross-Sectional Study"}]}, "item_type_id": "2", "owner": "6", "path": ["9"], "permalink_uri": "http://hdl.handle.net/10069/00041865", "pubdate": {"attribute_name": "公開日", "attribute_value": "2022-11-08"}, "publish_date": "2022-11-08", "publish_status": "0", "recid": "27730", "relation": {}, "relation_version_is_last": true, "title": ["VEGF Polymorphism rs3025039 and Human T-Cell Leukemia Virus 1 (HTLV-1) Infection among Older Japanese Individuals: A Cross-Sectional Study"], "weko_shared_id": -1}
VEGF Polymorphism rs3025039 and Human T-Cell Leukemia Virus 1 (HTLV-1) Infection among Older Japanese Individuals: A Cross-Sectional Study
http://hdl.handle.net/10069/00041865
http://hdl.handle.net/10069/00041865f5c0b83c-3800-4878-bba4-c1ca5abcfa51
名前 / ファイル | ライセンス | アクション |
---|---|---|
B9_527.pdf (254.5 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2022-11-08 | |||||
タイトル | ||||||
タイトル | VEGF Polymorphism rs3025039 and Human T-Cell Leukemia Virus 1 (HTLV-1) Infection among Older Japanese Individuals: A Cross-Sectional Study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | angiogenesis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HTLV-1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | rs3025039 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | SNP | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | VEGF | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Shimizu, Yuji
× Shimizu, Yuji× Yamanashi, Hirotomo× Miyata, Jun× Takada, Midori× Noguchi, Yuko× Honda, Yukiko× Nonaka, Fumiaki× Nakamichi, Seiko× Nagata, Yasuhiro× Maeda, Takahiro |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Previous studies have reported a close correlation between vascular endothelial growth factor (VEGF), which plays an important role in angiogenesis, and human T-cell leukemia virus 1 (HTLV-1). However, an association between genetic characteristics related to VEGF and HTLV-1 infection has not yet been reported. Because the VEGF polymorphism rs3025039 is inversely associated with serum concentrations of VEGF, we focus on rs3025039 in the present study. To clarify the association between the VEGF polymorphism rs3025039 and HTLV-1 infection, a cross-sectional study of 1924 Japanese individuals aged 60–79 years who participated in general health check-ups was conducted. Using logistic regression, odds ratios (ORs) and 95% confidence intervals (CIs) for HTLV-1 infection in relation to rs3025039 genotype were calculated with adjustment for known confounders. Compared with rs3025039 CC-homozygotes, (T) allele carriers had a significantly lower OR for HTLV-1 infection. The adjusted OR and 95% CI for HTLV-1 infection was 0.70 (0.54–0.91) (p = 0.009). Genetic characteristics related to lower angiogenesis activity might be associated with a lower chance of establishing HTLV-1 infection. Although further investigation is necessary, angiogenesis might play a crucial role in the establishment of HTLV-1 infection. | |||||
書誌情報 |
Bioengineering 巻 9, 号 10, p. 527, 発行日 2022-10-06 |
|||||
出版者 | ||||||
出版者 | MDPI | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 2306-5354 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3390/bioengineering9100527 | |||||
権利 | ||||||
権利情報 | © 2022 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license (https://creativecommons.org/licenses/by/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Bioengineering, 9(10), art. no. 527; 2022 |