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Seroepidemiology and Carriage of Diphtheria in Epidemic-Prone Area and Implications for Vaccination Policy, Vietnam
http://hdl.handle.net/10069/00041956
http://hdl.handle.net/10069/00041956368acc41-c530-4867-9e51-5aa420c76ab3
名前 / ファイル | ライセンス | アクション |
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EID29_70.pdf (1.4 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2023-01-13 | |||||
タイトル | ||||||
タイトル | Seroepidemiology and Carriage of Diphtheria in Epidemic-Prone Area and Implications for Vaccination Policy, Vietnam | |||||
言語 | ||||||
言語 | eng | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kitamura, Noriko
× Kitamura, Noriko× Hoan, Thanh T.× Do, Hung M.× Dao, The A.× Le, Lien T.× Le, Thao T.T.× Doan, Thuy T.T.× Chau, Thuong N.× Dinh, Hoi T.× Iwaki, Masaaki× Senoh, Mitsutoshi× Efstraciou, Androulla× Ho, Nen M.× Pham, Duc M.× Dang, Duc-Anh× Toizumi, Michiko× Fine, Paul× Do, Hung T.× Yoshida, Lay-Myint |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | In 2019, a community-based, cross-sectional carriage survey and a seroprevalence survey of 1,216 persons 1–55 years of age were conducted in rural Vietnam to investigate the mechanism of diphtheria outbreaks. Seroprevalence was further compared with that of an urban area that had no cases reported for the past decade. Carriage prevalence was 1.4%. The highest prevalence, 4.5%, was observed for children 1–5 years of age. Twenty-seven asymptomatic Coerynebacterium diphtheriae carriers were identified; 9 carriers had tox gene–bearing strains, and 3 had nontoxigenic tox gene–bearing strains. Child malnutrition was associated with low levels of diphtheria toxoid IgG, which might have subsequently increased child carriage prevalence. Different immunity patterns in the 2 populations suggested that the low immunity among children caused by low vaccination coverage increased transmission, resulting in symptomatic infections at school-going age, when vaccine-induced immunity waned most. A school-entry booster dose and improved infant vaccination coverage are recommended to control transmissions. | |||||
書誌情報 |
Emerging Infectious Diseases 巻 29, 号 1, p. 70-80, 発行日 2022-12-17 |
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出版者 | ||||||
出版者 | Centers for Disease Control and Prevention (CDC) | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 1080-6040 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.3201/eid2901.220975 | |||||
権利 | ||||||
権利情報 | Emerging Infectious Diseases is an open access journal in the public domain. All content is freely available without charge to users or their institutions. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Emerging Infectious Diseases, 29(1), pp.70-80; 2022 |