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Effect of Vancomycin and Glucose on Biofilm Formation by Coagulase-negative Staphylococci: Investigation of Standard Strains and Clinical Strains isolated from Implant-related Infection
http://hdl.handle.net/10069/38192
http://hdl.handle.net/10069/38192e960f0cd-1bde-40b5-8bdf-f01d8905b97a
| 名前 / ファイル | ライセンス | アクション |
|---|---|---|
ActMed61_159.pdf (801.3 kB)
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| Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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| 公開日 | 2018-05-10 | |||||
| タイトル | ||||||
| タイトル | Effect of Vancomycin and Glucose on Biofilm Formation by Coagulase-negative Staphylococci: Investigation of Standard Strains and Clinical Strains isolated from Implant-related Infection | |||||
| 言語 | ||||||
| 言語 | eng | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | coagulase-negative staphylococci | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | biofilm | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | biofilm coverage rate (BCR) | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | vancomycin | |||||
| キーワード | ||||||
| 主題Scheme | Other | |||||
| 主題 | glucose | |||||
| 資源タイプ | ||||||
| 資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
| 資源タイプ | departmental bulletin paper | |||||
| 著者 |
Adachi, Shinji
× Adachi, Shinji× Yonekura, Akihiko× Sakimura, Toshiyuki× Kajiyama, Shiro× Tomita, Masato× Tsurumoto, Toshiyuki× Osaki, Makoto |
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| 抄録 | ||||||
| 内容記述タイプ | Abstract | |||||
| 内容記述 | [Objective] The objective of this study was to investigate the suppressive effect of antibiotics and presence or absence of glucose on biofilm formation on metal surfaces by coagulase-negative Staphylococci. [Materials and Methods] Bacterial strains included a standard biofilm-forming strain of Staphylococcus epidermidis, nonbiofilm-forming strain of Staphylococcus hominis, and two clinical strains of Staphylococcus epidermidis isolated from implantrelated infection (IRI). Vancomycin (VCM) was used as the antibiotic. Trypticase soy broth (TSB) and TSB without dextrose (TSB w/o D) were used as growth media. Each strain was adhered to stainless steel washers and cultured in different growth media with various VCM concentrations for different lengths of time. The degree of biofilm formation was measured as the biofilm coverage rate (BCR). [Results] BCR decreased with increasing VCM concentration and shorter incubation time; however, the degree of suppression varied by strain. BCR was lower for strains cultured in TSB w/o D than for those in TSB. BCR for 8-h incubation group was significantly reduced at lower VCM concentrations in TSB w/o D than in TSB. [Conclusions] Biofilm formation was suppressed in absence of glucose environments, suggesting the importance of controlling blood glucose levels during the perioperative period to prevent IRI. |
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| 書誌情報 |
Acta medica Nagasakiensia 巻 61, 号 4, p. 159-166, 発行日 2018-03 |
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| ISSN | ||||||
| 収録物識別子タイプ | ISSN | |||||
| 収録物識別子 | 00016055 | |||||
| 書誌レコードID | ||||||
| 収録物識別子タイプ | NCID | |||||
| 収録物識別子 | AA00508430 | |||||
| 著者版フラグ | ||||||
| 出版タイプ | VoR | |||||
| 出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
| 出版者 | ||||||
| 出版者 | Nagasaki University School of Medicine | |||||
| 出版者別言語 | ||||||
| 値 | 長崎大学医学部 | |||||
| sortkey | ||||||
| 値 | 04 | |||||
| 引用 | ||||||
| 内容記述タイプ | Other | |||||
| 内容記述 | Acta medica Nagasakiensia, 61(4), pp.159-166; 2018 | |||||
