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Smoking is a risk factor for development of adult T-cell leukemia/lymphoma in Japanese human T-cell leukemia virus type-1 carriers
http://hdl.handle.net/10069/36933
http://hdl.handle.net/10069/36933b027b8f2-28ca-4784-bf1a-4559ac55c1b9
名前 / ファイル | ライセンス | アクション |
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CCC27_1059.pdf (261.1 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2017-10-01 | |||||
タイトル | ||||||
タイトル | Smoking is a risk factor for development of adult T-cell leukemia/lymphoma in Japanese human T-cell leukemia virus type-1 carriers | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ATLL | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cigarette smoking | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | HTLV-1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Japanese | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Kondo, Hisayoshi
× Kondo, Hisayoshi× Soda, Midori× Sawada, Norie× Inoue, Manami× Imaizumi, Yoshitaka× Miyazaki, Yasushi× Iwanaga, Masako× Tanaka, Yasuhito× Mizokami, Masashi× Tsugane, Shoichiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background and purpose: Adult T-cell leukemia/lymphoma (ATLL) is an aggressive hematological malignancy caused by human T-cell leukemia virus type-1 (HTLV-1); no effective methods have yet been identified to prevent development of ATLL in carriers of HTLV-1. This study investigated the association between cigarette smoking and the risk of ATLL development among Japanese carriers of HTLV-1. Methods: This study examined the association between smoking and development of ATLL in a cohort of 1,332 Japanese HTLV-1 carriers aged 40?69 years free of ATLL at baseline from two different HTLV-1-endemic areas of Japan. Cox proportional hazards models adjusted for sex, geographic area, age at baseline, and alcohol drinking were used to estimate the effect of cigarette smoking on ATLL development. Results: Between 1993 and 2012, 25 new ATLL cases were identified among these subjects. The overall crude incidence rate for ATLL was 1.08 per 1,000 person-years among HTLV-1 carriers and was higher among male carriers than among female carriers (2.21 vs. 0.74). The risk of ATLL development increased significantly with increasing numbers of cigarettes smoked per day (hazard ratio for every increment of 20 cigarettes, 2.03; 95 % confidence interval (CI) 1.13?3.66 overall, 2.07 (95 % CI 1.13?3.73) in male carriers). Conclusions: Cigarette smoking may influence ATLL development among HTLV-1 carriers in Japan. | |||||
書誌情報 |
Cancer Causes & Control 巻 27, 号 9, p. 1059-1066, 発行日 2016-09 |
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出版者 | ||||||
出版者 | Springer International Publishing Switzerland | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09575243 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 15737225 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1007/s10552-016-0784-8 | |||||
権利 | ||||||
権利情報 | c Springer International Publishing Switzerland 2016 | |||||
権利 | ||||||
権利情報 | The final publication is available at link.springer.com | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Cancer Causes & Control, 27(9), pp.1059-1066; 2016 |