WEKO3
アイテム
{"_buckets": {"deposit": "050d5d84-c799-49bf-a80f-66b24a7845b1"}, "_deposit": {"created_by": 2, "id": "3786", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "3786"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00003786", "sets": ["30"]}, "author_link": ["15405", "15402", "15411", "15403", "15408", "15401", "15409", "15412", "15399", "15406", "15404", "15398", "15400", "15410", "15407"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2016-02", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "189", "bibliographicPageStart": "184", "bibliographicVolumeNumber": "42", "bibliographic_titles": [{"bibliographic_title": "European Journal of Surgical Oncology"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background/Aim: The Kyushu Study Group of Clinical Cancer (KSCC) previously reported the safety and efficacy of neoadjuvant chemotherapy with mFOLFOX6 + bevacizumab for H2/H3 liver metastases of colorectal cancer. The aim of the current study was to evaluate the resectability of these metastases before and after chemotherapy as determined by independent liver surgeons. Methods: Between May 2008 and April 2010, 40 patients were registered in a multicenter phase 2 trial of neoadjuvant chemotherapy (KSCC 0802). In Study 1, 5 independent liver surgeons from five different KSCC centers evaluated the resectability of liver metastases of colorectal cancer based on imaging studies performed before and after chemotherapy. Each surgeon was blinded to the other surgeons\u0027 evaluations. In addition, no information about the patients\u0027 characteristics was provided. In Study 2, 3 surgeons evaluated the resectability of these lesions based on imaging studies with discussion with each other, with the surgeons being provided with information on the patients\u0027 characteristics. Results: In Study 1, 13 patients (36.1%) were evaluated to be resectable at baseline, whereas 17 patients (47.2%) were evaluated to be resectable after chemotherapy. In Study 2, 4 patients (11.1%) were evaluated to be resectable at baseline, compared to 23 patients (63.9%) after chemotherapy. Conclusion: Neoadjuvant chemotherapy with mFOLFOX6 + bevacizumab was confirmed to increase the resectability of non-resectable liver metastases of colorectal cancer according to the independent assessments of surgeons.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "European Journal of Surgical Oncology, 42(2), pp.184-189; 2016", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier Ltd."}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.ejso.2015.11.007", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "07487983", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Takatsuki, Mitsuhisa"}], "nameIdentifiers": [{"nameIdentifier": "15398", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Tokunaga, Shoji"}], "nameIdentifiers": [{"nameIdentifier": "15399", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Uchida, Shinji"}], "nameIdentifiers": [{"nameIdentifier": "15400", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Sakoda, Masahiko"}], "nameIdentifiers": [{"nameIdentifier": "15401", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Shirabe, Ken"}], "nameIdentifiers": [{"nameIdentifier": "15402", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Beppu, Toru"}], "nameIdentifiers": [{"nameIdentifier": "15403", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Emi, Yasunori"}], "nameIdentifiers": [{"nameIdentifier": "15404", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Oki, Eiji"}], "nameIdentifiers": [{"nameIdentifier": "15405", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ueno, Shinichi"}], "nameIdentifiers": [{"nameIdentifier": "15406", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Eguchi, Susumu"}], "nameIdentifiers": [{"nameIdentifier": "15407", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Akagi, Yoshito"}], "nameIdentifiers": [{"nameIdentifier": "15408", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Ogata, Yutaka"}], "nameIdentifiers": [{"nameIdentifier": "15409", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Baba, Hideo"}], "nameIdentifiers": [{"nameIdentifier": "15410", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Natsugoe, Shoji"}], "nameIdentifiers": [{"nameIdentifier": "15411", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Maehara, Yoshihiko"}], "nameIdentifiers": [{"nameIdentifier": "15412", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "EJSO42_184.pdf", "filesize": [{"value": "318.3 kB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 318300.0, "url": {"label": "EJSO42_184.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/3786/files/EJSO42_184.pdf"}, "version_id": "ec0bc362-f5b3-4089-9b1b-e40efbe7bd15"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Liver metastasis", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Colorectal cancer", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Liver resection", "subitem_subject_scheme": "Other"}, {"subitem_subject": "mFOLFOX6", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Bevacizumab", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Conversion", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Neoadjuvant chemotherapy", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study"}]}, "item_type_id": "2", "owner": "2", "path": ["30"], "permalink_uri": "http://hdl.handle.net/10069/36968", "pubdate": {"attribute_name": "公開日", "attribute_value": "2017-03-01"}, "publish_date": "2017-03-01", "publish_status": "0", "recid": "3786", "relation": {}, "relation_version_is_last": true, "title": ["Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study"], "weko_shared_id": -1}
Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study
http://hdl.handle.net/10069/36968
http://hdl.handle.net/10069/36968cddff9a5-5df6-4d1a-b9d8-e84cd6e81c37
名前 / ファイル | ライセンス | アクション |
---|---|---|
EJSO42_184.pdf (318.3 kB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2017-03-01 | |||||
タイトル | ||||||
タイトル | Evaluation of resectability after neoadjuvant chemotherapy for primary non-resectable colorectal liver metastases: A multicenter study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Liver metastasis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Colorectal cancer | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Liver resection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mFOLFOX6 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Bevacizumab | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Conversion | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Neoadjuvant chemotherapy | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takatsuki, Mitsuhisa
× Takatsuki, Mitsuhisa× Tokunaga, Shoji× Uchida, Shinji× Sakoda, Masahiko× Shirabe, Ken× Beppu, Toru× Emi, Yasunori× Oki, Eiji× Ueno, Shinichi× Eguchi, Susumu× Akagi, Yoshito× Ogata, Yutaka× Baba, Hideo× Natsugoe, Shoji× Maehara, Yoshihiko |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background/Aim: The Kyushu Study Group of Clinical Cancer (KSCC) previously reported the safety and efficacy of neoadjuvant chemotherapy with mFOLFOX6 + bevacizumab for H2/H3 liver metastases of colorectal cancer. The aim of the current study was to evaluate the resectability of these metastases before and after chemotherapy as determined by independent liver surgeons. Methods: Between May 2008 and April 2010, 40 patients were registered in a multicenter phase 2 trial of neoadjuvant chemotherapy (KSCC 0802). In Study 1, 5 independent liver surgeons from five different KSCC centers evaluated the resectability of liver metastases of colorectal cancer based on imaging studies performed before and after chemotherapy. Each surgeon was blinded to the other surgeons' evaluations. In addition, no information about the patients' characteristics was provided. In Study 2, 3 surgeons evaluated the resectability of these lesions based on imaging studies with discussion with each other, with the surgeons being provided with information on the patients' characteristics. Results: In Study 1, 13 patients (36.1%) were evaluated to be resectable at baseline, whereas 17 patients (47.2%) were evaluated to be resectable after chemotherapy. In Study 2, 4 patients (11.1%) were evaluated to be resectable at baseline, compared to 23 patients (63.9%) after chemotherapy. Conclusion: Neoadjuvant chemotherapy with mFOLFOX6 + bevacizumab was confirmed to increase the resectability of non-resectable liver metastases of colorectal cancer according to the independent assessments of surgeons. | |||||
書誌情報 |
European Journal of Surgical Oncology 巻 42, 号 2, p. 184-189, 発行日 2016-02 |
|||||
出版者 | ||||||
出版者 | Elsevier Ltd. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 07487983 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.ejso.2015.11.007 | |||||
権利 | ||||||
権利情報 | c 2015. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | European Journal of Surgical Oncology, 42(2), pp.184-189; 2016 |