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However, Japan\u0027s sex culture is so closed that it is difficult to test this possibility without accumulating scientific evidence. Therefore, it is necessary to measure the concentration of sex-related hormones in saliva, an experimental technique that is relatively easy to obtain research permission, and to obtain a scientific basis to convince ethics committee reviewers. Aim: The aim of this study is to investigate whether β-caryophyllene increases salivary testosterone concentrations associated with libido and vaginal sensation ]during intercourse in women. Methods: 19 women in the follicular phase of the menstrual cycle participated in the study.The subjects then sat in front of the odor exposure device we had created. Each subject was exposed to dipropylene glycol for 20 minutes, followed by 3% β-caryophyllene for 20 minutes. Saliva was collected 4 times: before and after control exposure, and before and after β-caryophyllene exposure. Main Outcome Measure: Salivary testosterone and estrogen concentrations were measured with a competition ELISA. Results: β-caryophyllene significantly increased the salivary concentration of testosterone(control vs β-caryophyllene; 0.97 ± 0.05 vs 1.13 ± 0.03, P = .00, 95% confidence interval of control: 0.84?1.09, 95% confidence interval of β-caryophyllene: 1.04?1.20) but not estrogen (control vs β-caryophyllene; 1.05 ± 0.03 vs 1.07 ± 0.04, P = .69, 95% confidence interval of control: 0.96?1.12, 95% confidence interval of β-caryophyllene: 0.98?1.15). Strengths \u0026 Limitations: The personal\n preferences of the subjects and the order of exposure may have affected the results. Conclusion: β-caryophyllene may be a remedy\n with fewer side effects for women with decreased libido. We believe that β-caryophyllene may be a remedy for women \nwith decreased libido. However, this hypothesis must be tested by further clinical studies. Wataru Tarumi, Kazuyuki Shinohara. Olfactory Exposure to β-Caryophyllene Increases Testosterone Levels in Women\u0027s Saliva. J Sex Med 2020;8:525?53", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Sexual Medicine, 8(3), pp.525-531; 2020", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Elsevier Inc."}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isIdenticalTo", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.esxm.2020.06.001", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c2020, The Authors. Published by Elsevier Inc. on behalf of the International Society for Sexual Medicine. 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Olfactory Exposure to β-Caryophyllene Increases Testosterone Levels in Women's Saliva
http://hdl.handle.net/10069/40265
http://hdl.handle.net/10069/402656abcb0ed-ab18-4427-a432-98d947226838
名前 / ファイル | ライセンス | アクション |
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SexMed8_525.pdf (469.5 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2020-09-18 | |||||
タイトル | ||||||
タイトル | Olfactory Exposure to β-Caryophyllene Increases Testosterone Levels in Women's Saliva | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Aphrodisiac | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pheromone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Sexuality | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Testosterone | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Ylang-ylang | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | β-caryophyllene | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tarumi, Wataru
× Tarumi, Wataru× Shinohara, Kazuyuki |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Introduction: From previous studies, we hypothesized that olfactory exposure to β-caryophyllene stimulates women's libido. However, Japan's sex culture is so closed that it is difficult to test this possibility without accumulating scientific evidence. Therefore, it is necessary to measure the concentration of sex-related hormones in saliva, an experimental technique that is relatively easy to obtain research permission, and to obtain a scientific basis to convince ethics committee reviewers. Aim: The aim of this study is to investigate whether β-caryophyllene increases salivary testosterone concentrations associated with libido and vaginal sensation ]during intercourse in women. Methods: 19 women in the follicular phase of the menstrual cycle participated in the study.The subjects then sat in front of the odor exposure device we had created. Each subject was exposed to dipropylene glycol for 20 minutes, followed by 3% β-caryophyllene for 20 minutes. Saliva was collected 4 times: before and after control exposure, and before and after β-caryophyllene exposure. Main Outcome Measure: Salivary testosterone and estrogen concentrations were measured with a competition ELISA. Results: β-caryophyllene significantly increased the salivary concentration of testosterone(control vs β-caryophyllene; 0.97 ± 0.05 vs 1.13 ± 0.03, P = .00, 95% confidence interval of control: 0.84?1.09, 95% confidence interval of β-caryophyllene: 1.04?1.20) but not estrogen (control vs β-caryophyllene; 1.05 ± 0.03 vs 1.07 ± 0.04, P = .69, 95% confidence interval of control: 0.96?1.12, 95% confidence interval of β-caryophyllene: 0.98?1.15). Strengths & Limitations: The personal preferences of the subjects and the order of exposure may have affected the results. Conclusion: β-caryophyllene may be a remedy with fewer side effects for women with decreased libido. We believe that β-caryophyllene may be a remedy for women with decreased libido. However, this hypothesis must be tested by further clinical studies. Wataru Tarumi, Kazuyuki Shinohara. Olfactory Exposure to β-Caryophyllene Increases Testosterone Levels in Women's Saliva. J Sex Med 2020;8:525?53 |
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書誌情報 |
Sexual Medicine 巻 8, 号 3, p. 525-531, 発行日 2020-06-16 |
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出版者 | ||||||
出版者 | Elsevier Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 20501161 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.esxm.2020.06.001 | |||||
権利 | ||||||
権利情報 | c2020, The Authors. Published by Elsevier Inc. on behalf of the International Society for Sexual Medicine. This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Sexual Medicine, 8(3), pp.525-531; 2020 |