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Many cross-sectional studies reported that air pollution caused respiratory disease in Japanese individuals in the 1960s. Japan has laws regulating air pollution levels and providing compensation for victims of pollution-related respiratory disease. However, long-term changes in respiratory function and symptoms in individuals who were exposed to air pollution in the 1960s have not been well studied. This study aimed to investigate longitudinal respiratory function and symptoms in older, non-smoking, long-term officially-acknowledged victims of pollution-related illness.\nMethods\nThe study included 563 officially-acknowledged victims of pollution-related illness living in Kurashiki, Okayama who were aged ? 65 years in 2009. Data were retrospectively collected from yearly respiratory symptom questionnaires and spirometry examinations conducted from 2000 to 2009.\nResults\nRespiratory function declined significantly from 2000 to 2009 (p \u003c 0.01), but the mean annual changes were relatively small. The change in mean vital capacity was ?40.5 ml/year in males and ?32.7 ml/year in females, and the change in mean forced expiratory volume in 1 second was ?27.6 ml/year in males and ?23.9 ml/year in females. Dyspnea was the only symptom that worsened significantly from 2000 to 2009 in both sexes (males: p \u003c 0.05, females: p \u003c 0.01).\nConclusions\nOur results suggest that the high concentrations of air pollutants around 1970 resulted in a decrease in respiratory function and an increase in respiratory symptoms in the study population. From 2000 to 2009, the mean annual changes in respiratory function were within the normal range, even though the severity of dyspnea worsened. 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Longitudinal study of respiratory function and symptoms in a non-smoking group of long-term officially-acknowledged victims of pollution-related illness
http://hdl.handle.net/10069/35408
http://hdl.handle.net/10069/354081baa007e-5304-4497-83cb-1a57e8474529
名前 / ファイル | ライセンス | アクション |
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ISYK665_Tanaka.pdf (3.3 MB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2015-05-28 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Longitudinal study of respiratory function and symptoms in a non-smoking group of long-term officially-acknowledged victims of pollution-related illness | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Air pollution | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pollution-related illness | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Respiratory function | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Respiratory symptoms | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Longitudinal study | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
田中, 貴子
× 田中, 貴子 |
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著者別名 | ||||||
姓名 | Tanaka, Takako | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background Air pollution is known to be a leading cause of respiratory symptoms. Many cross-sectional studies reported that air pollution caused respiratory disease in Japanese individuals in the 1960s. Japan has laws regulating air pollution levels and providing compensation for victims of pollution-related respiratory disease. However, long-term changes in respiratory function and symptoms in individuals who were exposed to air pollution in the 1960s have not been well studied. This study aimed to investigate longitudinal respiratory function and symptoms in older, non-smoking, long-term officially-acknowledged victims of pollution-related illness. Methods The study included 563 officially-acknowledged victims of pollution-related illness living in Kurashiki, Okayama who were aged ? 65 years in 2009. Data were retrospectively collected from yearly respiratory symptom questionnaires and spirometry examinations conducted from 2000 to 2009. Results Respiratory function declined significantly from 2000 to 2009 (p < 0.01), but the mean annual changes were relatively small. The change in mean vital capacity was ?40.5 ml/year in males and ?32.7 ml/year in females, and the change in mean forced expiratory volume in 1 second was ?27.6 ml/year in males and ?23.9 ml/year in females. Dyspnea was the only symptom that worsened significantly from 2000 to 2009 in both sexes (males: p < 0.05, females: p < 0.01). Conclusions Our results suggest that the high concentrations of air pollutants around 1970 resulted in a decrease in respiratory function and an increase in respiratory symptoms in the study population. From 2000 to 2009, the mean annual changes in respiratory function were within the normal range, even though the severity of dyspnea worsened. The changes in respiratory function and symptoms over the study period were probably due to aging. The laws governing air pollution levels and providing compensation for officially-acknowledged victims of pollution-related illness in Japan may be effective for respiratory disease cause by pollution. |
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内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 長崎大学学位論文 学位記番号:博(医歯薬)甲第665号 学位授与年月日:平成26年3月20日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Author: Takako Tanaka, Masaharu Asai, Yorihide Yanagita, Tsuyoshi Nishinakagawa, Naomi Miyamoto, Kenji Kotaki, Yudai Yano, Ryo Kozu, Sumihisa Honda, Hideaki Senjyu | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Citation: BMC Public Health, 13, 766; 2013 | |||||
書誌情報 |
BMC Public Health 巻 13, p. 766, 発行日 2014-03-20 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 14712458 | |||||
DOI | ||||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/1471-2458-13-766 | |||||
権利 | ||||||
権利情報 | c 2013 Tanaka et al.; licensee BioMed Central Ltd. | |||||
権利 | ||||||
権利情報 | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
その他のタイトル | 非喫煙公害認定患者における呼吸機能と呼吸器症状の縦断的研究 | |||||
出版者 | ||||||
出版者 | BioMed Central Ltd. | |||||
関係URI | ||||||
識別子タイプ | HDL | |||||
関連識別子 | http://hdl.handle.net/10069/34613 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 17301 | |||||
学位授与機関名 | Nagasaki University (長崎大学) | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2014-03-20 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲医歯薬第665号 | |||||
学位の種類 | ||||||
課程博士 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Nagasaki University (長崎大学), 博士(医学) (2014-03-20) |