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Presentation of case A 43-year-old female, who had undergone surgery to treat a GCT of the left ovary in 1976, complained of abdominal distention in May 2001. Imaging studies demonstrated masses in the right lobe of the liver, together with massive ascites. The patient\u0027s bloody ascites showed no cytological evidence of malignancy. A diagnostic laparoscopy was performed, and the biopsy specimen was histologically proven to be a recurrent granulosa cell tumor. The patient was successfully treated surgery followed by systemic chemotherapy. Her postoperative course was uneventful and systemic chemotherapy was repeated due to the suspicion of a recurrence in the pelvic cavity. Discussion GCTs which are rare malignant tumors of the ovary, tend to be associated with late recurrence. Although most recurrences occur within 10 years after the initial diagnosis, there are occasional reports of recurrences after 10 years have been. We experienced the rare case of a patient who relapsed 25 years after the initial diagnosis. Conclusion The long natural history of this disease highlights the importance of extended follow up for GCT patients. 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A recurrent granulosa cell tumor of the ovary 25 years after the initial diagnosis: A case report
http://hdl.handle.net/10069/35483
http://hdl.handle.net/10069/35483f0957f4d-75f7-42a8-b689-964b4b8801a2
名前 / ファイル | ライセンス | アクション |
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IJSCR12_7.pdf (2.2 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-06-17 | |||||
タイトル | ||||||
タイトル | A recurrent granulosa cell tumor of the ovary 25 years after the initial diagnosis: A case report | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Diagnostic laparoscopy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Granulosa cell tumor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Metastatic liver tumor | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Recurrence | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Fujita, Fumihiko
× Fujita, Fumihiko× Eguchi, Susumu× Takatsuki, Mitsuhisa× Kobayashi, Kazuma× Kanetaka, Kengo× Ito, Masahiro× Abe, Kuniko× Kuroki, Tamotsu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Introduction Granulosa cell tumors (GCTs) are rare functional sex-cord-stromal ovarian neoplasms characterized by low malignancy potential and late relapse, which rarely metastasize to the liver. Presentation of case A 43-year-old female, who had undergone surgery to treat a GCT of the left ovary in 1976, complained of abdominal distention in May 2001. Imaging studies demonstrated masses in the right lobe of the liver, together with massive ascites. The patient's bloody ascites showed no cytological evidence of malignancy. A diagnostic laparoscopy was performed, and the biopsy specimen was histologically proven to be a recurrent granulosa cell tumor. The patient was successfully treated surgery followed by systemic chemotherapy. Her postoperative course was uneventful and systemic chemotherapy was repeated due to the suspicion of a recurrence in the pelvic cavity. Discussion GCTs which are rare malignant tumors of the ovary, tend to be associated with late recurrence. Although most recurrences occur within 10 years after the initial diagnosis, there are occasional reports of recurrences after 10 years have been. We experienced the rare case of a patient who relapsed 25 years after the initial diagnosis. Conclusion The long natural history of this disease highlights the importance of extended follow up for GCT patients. In addition, aggressive therapy including surgery and chemotherapy may contribute to a patient's long-term prognosis. | |||||
書誌情報 |
International Journal of Surgery Case Reports 巻 12, p. 7-10, 発行日 2015-05-07 |
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出版者 | ||||||
出版者 | Elsevier Ltd | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 22102612 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.ijscr.2015.05.004 | |||||
権利 | ||||||
権利情報 | c 2015 The Authors. Published by Elsevier Ltd. on behalf of Surgical Associates Ltd. | |||||
権利 | ||||||
権利情報 | This is an openaccess article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/). | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | International Journal of Surgery Case Reports, 12, pp.7-10; 2015 |