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Infectious Episodes Lead to the Oxidative Stress Response after Lung Transplantation
http://hdl.handle.net/10069/35486
http://hdl.handle.net/10069/354868636e3cd-4246-4f69-9175-0e4395b7a520
名前 / ファイル | ライセンス | アクション |
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AJCR16_255.pdf (372.7 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-06-17 | |||||
タイトル | ||||||
タイトル | Infectious Episodes Lead to the Oxidative Stress Response after Lung Transplantation | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Immunosuppression | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Lung transplantation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Oxidative stress | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Takuro, Miyazaki
× Takuro, Miyazaki× Naoya, Yamasaki× Tomoshi, Tsuchiya× Keitaro, Matsumoto× Katsunori, Takagi× Hiroo, Izumino× Takeshi, Nagayasu |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Objective: Challenging differential diagnosis Background: Reactive oxygen species function as key metabolites that can impair biological processes. In lung transplantation, severe oxidative stress is expected when ischemia/reperfusion injury, acute allograft rejection, and various infections occur. Case Report: Two clinical cases in which serial measurements of the oxidative stress response (levels of diacron-reactive oxygen metabolites) were taken during hospitalization using a Free Radical Elective Evaluator are reported. In the first case, a 30-year-old man underwent right single lung transplantation for juvenile pulmonary emphysema. Immunosuppression was maintained using tacrolimus, mycophenolate mofetil, and steroid. The oxidative stress response fluctuated significantly (p<0.01) during the infections caused by bronchial stenosis compared to the stable condition. No acute rejection was seen during hospitalization. In the second case, a 44-year-old woman underwent right single lung transplantation for lymphangioleiomyomatosis. Immunosuppression was maintained by the same regimen as in case 1. The patient’s postoperative course was uneventful, and there was no allograft rejection or infection. The oxidative stress response remained at the non-stress level. Conclusions: The oxidative stress response was measured by the levels of diacron-reactive oxygen metabolites in lung transplantation. High oxidative stress responses were seen during exposure to infections. This might become a noninvasive marker of complications after transplantation. | |||||
書誌情報 |
American Journal of Case Reports 巻 16, p. 255-258, 発行日 2015-04-30 |
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出版者 | ||||||
出版者 | International Scientific Literature, Inc | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 19415923 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.12659/AJCR.893026 | |||||
権利 | ||||||
権利情報 | c International Scientific Information | |||||
権利 | ||||||
権利情報 | This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivs 3.0 Unported License. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | American Journal of Case Reports, 16, pp.255-258; 2015 |