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Hand Osteolysis in Patients with Adult T-Cell Leukemia-Lymphoma: Radiographic Characteristics
http://hdl.handle.net/10069/35492
http://hdl.handle.net/10069/35492ae745ae0-19e1-477c-8801-580fa6b7e8d6
名前 / ファイル | ライセンス | アクション |
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TJEM236_63.pdf (1.0 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-06-18 | |||||
タイトル | ||||||
タイトル | Hand Osteolysis in Patients with Adult T-Cell Leukemia-Lymphoma: Radiographic Characteristics | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Adult T-cell leukemia-lymphoma | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hyperparathyroidism | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Osteolysis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Parathyroid hormone-related peptide | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Radiography | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Ehara, Shigeru
× Ehara, Shigeru× Takahashi, Kei× Nishida, Jun× Uetani, Masataka× Ohashi, Kenjirou× Aoki, Takatoshi |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Adult T-cell leukemia-lymphoma (ATLL) is caused by human T-cell lymphotrophic virus I (HTLV-I) infection. Among ATLL cases, 70% of patients present with leukemia and the remaining patients present with lymphoma. Hand osteolysis in the patients with ATLL is considered as paraneoplastic syndrome and caused by parathyroid hormone-related peptide (PTHrP) released from tumor cells. Radiographic features are similar to hyperparathyroidism, but the distribution of osteolysis in hands appears to be slightly different with the authors’ experiences. The objective of this study was to identify radiographic characteristics of hand osteolysis associated with ATLL. We included six ATLL patients (5 men and 1 woman; age range, 45-71 years). All the patients presented with acute leukemia, and three were associated with hypercalcemia and pain in various locations including hands. Patterns of osteolysis on hand radiographs were evaluated and recorded independently by three musculoskeletal radiologists. We analyzed the distribution of the bone resorption in the ray distribution of the hand, finger predilection, and the difference between the ulnar and radial sides. The bone resorption was characterized by frequent involvement of the distal and proximal phalanges, predilection of ring fingers and prominent involvement on the ulnar side, compared with frequent involvement of proximal and middle phalanges, index and middle fingers, and on the radial side in the bone resorption of typical hyperparathyroidism. Such distribution may be a characteristic feature of hand osteolysis in patients with ATLL. The present findings are helpful for physicians to differentiate PTHrP-mediated osteolysis in ATLL from parathyroid hormone-mediated hyperparathyroidism. | |||||
書誌情報 |
The Tohoku Journal of Experimental Medicine 巻 236, 号 1, p. 63-69, 発行日 2015-05-15 |
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出版者 | ||||||
出版者 | 東北ジャーナル刊行会 | |||||
出版者別言語 | ||||||
Tohoku University Medical Press | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00408727 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13493329 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1620/tjem.236.63 | |||||
権利 | ||||||
権利情報 | c 2015 Tohoku University Medical Press | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | The Tohoku Journal of Experimental Medicine, 236(1), pp.63-69; 2015 |