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Cutaneous Leishmaniasis in dogs: is high seroprevalence indicative of a reservoir role?
http://hdl.handle.net/10069/35644
http://hdl.handle.net/10069/35644f240a331-e626-4a02-9e5e-33fd9eef727f
名前 / ファイル | ライセンス | アクション |
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Par142_1202.pdf (320.3 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2015-07-15 | |||||
タイトル | ||||||
タイトル | Cutaneous Leishmaniasis in dogs: is high seroprevalence indicative of a reservoir role? | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Canis familiaris | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Leishmania panamensis | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | reservoirs | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | endemicity | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | force of infection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | catalytic models | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Calzada, Jose E.
× Calzada, Jose E.× Saldana, Azael× Gonzalez, Kadir× Rigg, Chystrie× Pineda, Vanessa× Santamaria, Ana Maria× Rodriguez, Indra× Gottdenker, Nicole L.× Laurenti, Marcia D.× Chaves, Luis Fernando |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | American cutaneous leishmaniasis (ACL) is a complex disease with a rich diversity of animal host species. This diversity imposes a challenge, since understanding ACL transmission requires the adequate identification of reservoir hosts, those species able to be a source of additional infections. In this study we present results from an ACL cross-sectional serological survey of 51 dogs (Canis familiaris), where we used diagnostic tests that measure dog's exposure to Leishmania spp. parasites. We did our research in Panama, at a village that has undergone significant ecosystem level transformations. We found an ACL seroprevalence of 47% among dogs, and their exposure was positively associated with dog age and abundance of sand fly vectors in the houses of dog owners. Using mathematical models, which were fitted to data on the proportion of positive tests as function of dog age, we estimated a basic reproductive number (R0 ± s.e.) of 1・22 ± 0・09 that indicates the disease is endemically established in the dogs. Nevertheless, this information by itself is insufficient to incriminate dogs as ACL reservoirs, given the inability to find parasites (or their DNA) in seropositive dogs and previously reported failures to experimentally infect vectors feeding on dogs with ACL parasites. | |||||
書誌情報 |
Parasitology 巻 142, 号 9, p. 1202-1214, 発行日 2015-08 |
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出版者 | ||||||
出版者 | Cambridge University Press | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00311820 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 14698161 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1017/S0031182015000475 | |||||
権利 | ||||||
権利情報 | c Cambridge University Press 2015 This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/3.0/), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Parasitology, 142(9), pp.1202-1214; 2015 |