WEKO3
アイテム
{"_buckets": {"deposit": "879e819b-500e-4dbd-85d9-4be84bbb1f46"}, "_deposit": {"created_by": 2, "id": "4740", "owners": [2], "pid": {"revision_id": 0, "type": "depid", "value": "4740"}, "status": "published"}, "_oai": {"id": "oai:nagasaki-u.repo.nii.ac.jp:00004740", "sets": ["9"]}, "author_link": ["19316", "19315", "19314", "19312", "19313"], "item_2_biblio_info_6": {"attribute_name": "書誌情報", "attribute_value_mlt": [{"bibliographicIssueDates": {"bibliographicIssueDate": "2015-05-15", "bibliographicIssueDateType": "Issued"}, "bibliographicIssueNumber": "2", "bibliographicPageEnd": "501", "bibliographicPageStart": "495", "bibliographicVolumeNumber": "195", "bibliographic_titles": [{"bibliographic_title": "Journal of Surgical Research"}]}]}, "item_2_description_4": {"attribute_name": "抄録", "attribute_value_mlt": [{"subitem_description": "Background Esophageal elongation by traction suture is used in pediatric patients to manage long-gap esophageal atresia (EA). There was no histological evidence of the esophageal elongation. Here, we sought to clarify the histologic effects of traction on the esophagus by using a rat EA model simulating Foker\u0027s method. Materials and methods Rats were randomly assigned into three groups (n = 5 each). The traction group underwent daily stretching of the distal segment of the esophagus. The nontraction group underwent a sham operation, and the normal group served as controls. Seven days after the operation, the distal segments of the esophagus were removed. The length and thickness were measured, and samples were stained with Ki-67, nNOS, and S-100. Results The whole length of the esophagus in the traction group was significantly longer than that in the nontraction group (P \u003c 0.01). The thickness of esophageal mucosa and muscle tended to become thin by traction, but not significantly. The Ki-67-positive ratio of mucosa and muscle was significantly higher in the traction group (P \u003c 0.05). There were no significant differences in Ki-67 between two segments (cardia-middle and middle-stump) in any group. Auerbach\u0027s plexus was identified at all sites of elongated esophagus by nNOS and S-100 staining. Conclusions By traction, the esophagus was elongated uniformly and cell proliferation activity was promoted in all parts of the elongated esophagus in the rat EA model.", "subitem_description_type": "Abstract"}]}, "item_2_description_63": {"attribute_name": "引用", "attribute_value_mlt": [{"subitem_description": "Journal of Surgical Research, 195(2), pp.495-501; 2015", "subitem_description_type": "Other"}]}, "item_2_publisher_33": {"attribute_name": "出版者", "attribute_value_mlt": [{"subitem_publisher": "Academic Press Inc."}]}, "item_2_relation_12": {"attribute_name": "DOI", "attribute_value_mlt": [{"subitem_relation_type": "isVersionOf", "subitem_relation_type_id": {"subitem_relation_type_id_text": "10.1016/j.jss.2015.02.010", "subitem_relation_type_select": "DOI"}}]}, "item_2_rights_13": {"attribute_name": "権利", "attribute_value_mlt": [{"subitem_rights": "c 2015 Elsevier Inc. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/"}]}, "item_2_source_id_7": {"attribute_name": "ISSN", "attribute_value_mlt": [{"subitem_source_identifier": "00224804", "subitem_source_identifier_type": "ISSN"}]}, "item_2_version_type_16": {"attribute_name": "著者版フラグ", "attribute_value_mlt": [{"subitem_version_resource": "http://purl.org/coar/version/c_ab4af688f83e57aa", "subitem_version_type": "AM"}]}, "item_creator": {"attribute_name": "著者", "attribute_type": "creator", "attribute_value_mlt": [{"creatorNames": [{"creatorName": "Inoue, Satoshi"}], "nameIdentifiers": [{"nameIdentifier": "19312", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kosaka, Taiichiro"}], "nameIdentifiers": [{"nameIdentifier": "19313", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Takatsuki, Mitsuhisa"}], "nameIdentifiers": [{"nameIdentifier": "19314", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Kuroki, Tamotsu"}], "nameIdentifiers": [{"nameIdentifier": "19315", "nameIdentifierScheme": "WEKO"}]}, {"creatorNames": [{"creatorName": "Eguchi, Susumu"}], "nameIdentifiers": [{"nameIdentifier": "19316", "nameIdentifierScheme": "WEKO"}]}]}, "item_files": {"attribute_name": "ファイル情報", "attribute_type": "file", "attribute_value_mlt": [{"accessrole": "open_date", "date": [{"dateType": "Available", "dateValue": "2020-12-21"}], "displaytype": "detail", "download_preview_message": "", "file_order": 0, "filename": "JSR195_495.pdf", "filesize": [{"value": "1.5 MB"}], "format": "application/pdf", "future_date_message": "", "is_thumbnail": false, "licensetype": "license_free", "mimetype": "application/pdf", "size": 1500000.0, "url": {"label": "JSR195_495.pdf", "url": "https://nagasaki-u.repo.nii.ac.jp/record/4740/files/JSR195_495.pdf"}, "version_id": "18d20a44-ac9c-4c50-ab25-f4f6467ed7db"}]}, "item_keyword": {"attribute_name": "キーワード", "attribute_value_mlt": [{"subitem_subject": "Esophageal atresia", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Esophageal elongation", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Esophagus", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Foker\u0027s method", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Long-gap", "subitem_subject_scheme": "Other"}, {"subitem_subject": "Proliferation", "subitem_subject_scheme": "Other"}]}, "item_language": {"attribute_name": "言語", "attribute_value_mlt": [{"subitem_language": "eng"}]}, "item_resource_type": {"attribute_name": "資源タイプ", "attribute_value_mlt": [{"resourcetype": "journal article", "resourceuri": "http://purl.org/coar/resource_type/c_6501"}]}, "item_title": "Histological study of the elongated esophagus in a rat model", "item_titles": {"attribute_name": "タイトル", "attribute_value_mlt": [{"subitem_title": "Histological study of the elongated esophagus in a rat model"}]}, "item_type_id": "2", "owner": "2", "path": ["9"], "permalink_uri": "http://hdl.handle.net/10069/35880", "pubdate": {"attribute_name": "公開日", "attribute_value": "2016-05-16"}, "publish_date": "2016-05-16", "publish_status": "0", "recid": "4740", "relation": {}, "relation_version_is_last": true, "title": ["Histological study of the elongated esophagus in a rat model"], "weko_shared_id": -1}
Histological study of the elongated esophagus in a rat model
http://hdl.handle.net/10069/35880
http://hdl.handle.net/10069/358807a684fc5-1d54-4636-b455-b77c2086413e
名前 / ファイル | ライセンス | アクション |
---|---|---|
JSR195_495.pdf (1.5 MB)
|
|
Item type | 学術雑誌論文 / Journal Article(1) | |||||
---|---|---|---|---|---|---|
公開日 | 2016-05-16 | |||||
タイトル | ||||||
タイトル | Histological study of the elongated esophagus in a rat model | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Esophageal atresia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Esophageal elongation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Esophagus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Foker's method | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Long-gap | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Proliferation | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Inoue, Satoshi
× Inoue, Satoshi× Kosaka, Taiichiro× Takatsuki, Mitsuhisa× Kuroki, Tamotsu× Eguchi, Susumu |
|||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background Esophageal elongation by traction suture is used in pediatric patients to manage long-gap esophageal atresia (EA). There was no histological evidence of the esophageal elongation. Here, we sought to clarify the histologic effects of traction on the esophagus by using a rat EA model simulating Foker's method. Materials and methods Rats were randomly assigned into three groups (n = 5 each). The traction group underwent daily stretching of the distal segment of the esophagus. The nontraction group underwent a sham operation, and the normal group served as controls. Seven days after the operation, the distal segments of the esophagus were removed. The length and thickness were measured, and samples were stained with Ki-67, nNOS, and S-100. Results The whole length of the esophagus in the traction group was significantly longer than that in the nontraction group (P < 0.01). The thickness of esophageal mucosa and muscle tended to become thin by traction, but not significantly. The Ki-67-positive ratio of mucosa and muscle was significantly higher in the traction group (P < 0.05). There were no significant differences in Ki-67 between two segments (cardia-middle and middle-stump) in any group. Auerbach's plexus was identified at all sites of elongated esophagus by nNOS and S-100 staining. Conclusions By traction, the esophagus was elongated uniformly and cell proliferation activity was promoted in all parts of the elongated esophagus in the rat EA model. | |||||
書誌情報 |
Journal of Surgical Research 巻 195, 号 2, p. 495-501, 発行日 2015-05-15 |
|||||
出版者 | ||||||
出版者 | Academic Press Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00224804 | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.jss.2015.02.010 | |||||
権利 | ||||||
権利情報 | c 2015 Elsevier Inc. Licensed under the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International http://creativecommons.org/licenses/by-nc-nd/4.0/ | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Surgical Research, 195(2), pp.495-501; 2015 |