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The purpose of this study is to evaluate the clinical characteristics and the pathohistological differences between BML and FED.Methods: A total of 73 patients who diagnosed as degenerative mitral valve disease pathologically after mitral valve surgery for severe mitral regurgitation were enrolled. On the basis of echocardiographic features and gross appearances, they were classified as BML (9 cases) and FED (64 cases).Results: In the BML group, multiple segments of the leaflet showed billowing with elongated chordae. Therefore excessive valve tissue needed to be removed by multiple resection and suture. The FED patients had focal myxomatous changes with ruptured chordae, a single resection and suture was frequently employed. 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Clinical and Pathological Features of Degenerative Mitral Valve Disease: Billowing Mitral Leaflet Versus Fibroelastic Deficiency
http://hdl.handle.net/10069/35893
http://hdl.handle.net/10069/35893a39cbda6-b8e0-45e2-af75-3b789d1da85c
名前 / ファイル | ライセンス | アクション |
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ISYK660_Matsumaru.pdf (990.1 kB)
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Item type | 学位論文 / Thesis or Dissertation(1) | |||||
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公開日 | 2015-10-20 | |||||
タイトル | ||||||
言語 | en | |||||
タイトル | Clinical and Pathological Features of Degenerative Mitral Valve Disease: Billowing Mitral Leaflet Versus Fibroelastic Deficiency | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | athology | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mitral valve | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mitral regurgitation | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mitral valve repair | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_db06 | |||||
資源タイプ | doctoral thesis | |||||
アクセス権 | ||||||
アクセス権 | open access | |||||
アクセス権URI | http://purl.org/coar/access_right/c_abf2 | |||||
著者 |
松丸, 一朗
× 松丸, 一朗 |
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著者別名 | ||||||
姓名 | Matsumaru, Ichiro | |||||
抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Purpose: Degenerative mitral valve disease is distinguished with billowing mitral leaflet (BML) or fibroelastic deficiency (FED). The purpose of this study is to evaluate the clinical characteristics and the pathohistological differences between BML and FED.Methods: A total of 73 patients who diagnosed as degenerative mitral valve disease pathologically after mitral valve surgery for severe mitral regurgitation were enrolled. On the basis of echocardiographic features and gross appearances, they were classified as BML (9 cases) and FED (64 cases).Results: In the BML group, multiple segments of the leaflet showed billowing with elongated chordae. Therefore excessive valve tissue needed to be removed by multiple resection and suture. The FED patients had focal myxomatous changes with ruptured chordae, a single resection and suture was frequently employed. In pathological examination, the valve thickness of the BML was nearly twice as thick as the FED, and the mucopolysaccharide accumulation of the Spongiosa in the BML was over 50%, while 30% in the FED.Conclusion: BML presents the characteristic valve thickening due to its abnormal production of mucopolysaccharide. Since excessive tissue was voluminous in the BML, high-grade plasty techniques, such as combination of multiple resection and chordal reconstruction were required. | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | 長崎大学学位論文 学位記番号:博(医歯薬)甲第660号 学位授与年月日:平成26年2月19日 | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Author: Ichiro Matsumaru, Kiyoyuki Eishi, Koji Hashizume, Hiroaki Kawano, Akira Tsuneto, Tomayoshi Hayashi | |||||
内容記述 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Citation: Annals of Thoracic and Cardiovascular Surgery, 20(6), pp.987-994; 2014 | |||||
書誌情報 |
Annals of Thoracic and Cardiovascular Surgery 巻 20, 号 6, p. 987-994, 発行日 2014-02-19 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 13411098 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 21861005 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.5761/atcs.oa.13-00168 | |||||
権利 | ||||||
権利情報 | c 2014 The Editorial Committee of Annals of Thoracic and Cardiovascular Surgery | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
その他のタイトル | ||||||
その他のタイトル | 粘液変性性僧帽弁疾患- Billowing Mitral LeafletとFibroelastic deficiency-臨床的および病理学的特徴 | |||||
出版者 | ||||||
出版者 | 日本冠動脈外科学会 | |||||
関係URI | ||||||
識別子タイプ | HDL | |||||
関連識別子 | http://hdl.handle.net/10069/34608 | |||||
学位名 | ||||||
学位名 | 博士(医学) | |||||
学位授与機関 | ||||||
学位授与機関識別子Scheme | kakenhi | |||||
学位授与機関識別子 | 17301 | |||||
学位授与機関名 | Nagasaki University (長崎大学) | |||||
学位授与年月日 | ||||||
学位授与年月日 | 2014-02-19 | |||||
学位授与番号 | ||||||
学位授与番号 | 甲医歯薬第660号 | |||||
学位の種類 | ||||||
課程博士 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Nagasaki University (長崎大学), 博士(医学) (2014-02-19) |