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Larval pufferfish protected by maternal tetrodotoxin
http://hdl.handle.net/10069/34069
http://hdl.handle.net/10069/3406945f27a5f-785e-43ab-b8f5-71e6c33efe63
名前 / ファイル | ライセンス | アクション |
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Toxicon78_35.pdf (1.1 MB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-01-24 | |||||
タイトル | ||||||
タイトル | Larval pufferfish protected by maternal tetrodotoxin | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Chemical defense | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pufferfish | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Survival strategy | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Takifugu | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Tetrodotoxin (TTX) | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Itoi, Shiro
× Itoi, Shiro× Yoshikawa, Saori× Asahina, Kiyoshi× Suzuki, Miwa× Ishizuka, Kento× Takimoto, Narumi× Mitsuoka, Ryoko× Yokoyama, Naoto× Detake, Ayumi× Takayanagi, Chie× Eguchi, Miho× Tatsuno, Ryohei× Kawane, Mitsuo× Kokubo, Shota× Takanashi, Shihori× Miura, Ai× Suitoh, Katsuyoshi× Takatani, Tomohiro× Arakawa, Osamu× Sakakura, Yoshitaka× Sugita, Haruo |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Marine pufferfish contain tetrodotoxin (TTX), an extremely potent neurotoxin. All species of the genus Takifugu accumulate TTX in the liver and ovaries, although the tissue(s) in which it is localized can differ among species. TTX is the major defense strategy the pufferfish appears to use against predators. TTX is also used as a male-attracting pheromone during spawning. Here we demonstrate an additional (and unexpected) use of maternal TTX in the early larval stages of the Takifugu pufferfish. Predation experiments demonstrated that juveniles of all the species of fish used as predators ingested pufferfish larvae, but spat them out promptly. Liquid Chromatography-Tandem Mass Spectrometry (LC-MSMS) analysis revealed that the pufferfish larvae contain a small quantity of TTX, which is not enough to be lethal to the predators. Immunohistochemical analysis with anti-TTX monoclonal antibody revealed that the TTX is primarily localized in the body surface of the larvae as a layer of protection. Our study showed the female parent of the Takifugu pufferfish vertically transfers TTX to the larvae through its accumulation in the ovaries, and subsequent localization on the body surface of the larvae. | |||||
書誌情報 |
Toxicon 巻 78, p. 35-40, 発行日 2014-02 |
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出版者 | ||||||
出版者 | Elsevier Limited | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00410101 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.toxicon.2013.11.003 | |||||
権利 | ||||||
権利情報 | c 2013 The Authors. Published by Elsevier Ltd. All rights reserved. | |||||
権利 | ||||||
権利情報 | This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-No Derivative Works License, which permits non-commercial use, distribution, and reproduction in any medium, provided the original author and source are credited. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Toxicon, 78, pp.35-40; 2014 |