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Association between Alkaline Phosphatase and Anemia in Rural Japanese Men: The Nagasaki Islands study
http://hdl.handle.net/10069/34224
http://hdl.handle.net/10069/34224ee9291f0-472f-4a80-96e1-0f5d6317ba87
名前 / ファイル | ライセンス | アクション |
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ActMed58_125.pdf (529.8 kB)
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Item type | 紀要論文 / Departmental Bulletin Paper(1) | |||||
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公開日 | 2014-04-02 | |||||
タイトル | ||||||
タイトル | Association between Alkaline Phosphatase and Anemia in Rural Japanese Men: The Nagasaki Islands study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | ALP | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | drinking status | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Anemia | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | cross-sectional study | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Men | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | departmental bulletin paper | |||||
著者 |
Shimizu, Yuji
× Shimizu, Yuji× Nakazato, Mio× Sekita, Takaharu× Kadota, Koichiro× Sato, Shimpei× Arima, Kazuhiko× Takamura, Noboru× Aoyagi, Kiyoshi× Kusano, Yosuke× Maeda, Takahiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Although bone metabolism is reportedly associated with production and maturation of blood corpuscles, and serum alkaline phosphatase (ALP) levels have been associated with bone metabolism, no published study has investigated the association between ALP and anemia. Furthermore, although ALP is known as an enzyme affected by alcohol consumption, there are no reports in the literature on associations between ALP and the risk of anemia in relation to drinking status. We conducted a cross-sectional study of 907 men aged 30-89 years undergoing a general health check-up to investigate the associations between ALP and anemia in relation to drinking status. Of the 907 participants, 120 men were diagnosed with anemia. The association between ALP and anemia was J-shaped. With the second quartile of ALP (194-228 IU/L) (Q2) as the reference group, the multivariable adjusted OR and 95%CI for anemia were 1.91 (95%CI: 0.96-3.82) for <194 IU/L (Q1), 1.84 (95%CI:0.93-3.62) for 229-277 IU/L (Q3) and 2.83 (95%CI:1.49-5.37) for >277 IU/L (Q4). When the analysis was limited to non-drinkers, the associations became stronger with corresponding values of 3.34 (95%CI: 1.28-8.74), 3.18 (95%CI: 1.28-7.88) and 3.22 (95%CI:1.37-7.59). Not only lower but also higher levels of serum ALP are associated with anemia for men, especially non-drinkers. For analyses of associations between ALP and anemia, alcohol consumption should thus be considered a potential confounder. | |||||
書誌情報 |
Acta medica Nagasakiensia 巻 58, 号 4, p. 125-130, 発行日 2014-03 |
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ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 00016055 | |||||
書誌レコードID | ||||||
収録物識別子タイプ | NCID | |||||
収録物識別子 | AA00508430 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
出版者 | ||||||
出版者 | Nagasaki University School of Medicine | |||||
出版者別言語 | ||||||
長崎大学医学部 | ||||||
sortkey | ||||||
4 | ||||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Acta medica Nagasakiensia, 58(4), pp.125-130; 2014 |