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Cofilin-1 is involved in regulation of actin reorganization during influenza A virus assembly and budding
http://hdl.handle.net/10069/34968
http://hdl.handle.net/10069/34968da58287d-48eb-4bc1-8973-b59b96ddcf6a
名前 / ファイル | ライセンス | アクション |
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BBRC453_821.pdf (542.8 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2014-12-24 | |||||
タイトル | ||||||
タイトル | Cofilin-1 is involved in regulation of actin reorganization during influenza A virus assembly and budding | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cofilin-1 | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | F-actin | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Influenza A virus | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Pentagalloyl glucose | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Viral assembly | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Viral budding | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Liu, Ge
× Liu, Ge× Xiang, Yangfei× Guo, Chaowan× Pei, Ying× Wang, Yifei× Kitazato, Kaio |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Influenza A virus (IAV) assembly and budding on host cell surface plasma membrane requires actin cytoskeleton reorganization. The underlying molecular mechanism involving actin reorganization remains unclarified. In this study, we found that the natural antiviral compound petagalloyl glucose (PGG) inhibits F-actin reorganization in the host cell membrane during the late stage of IAV infection, which are associated with the suppression of total cofilin-1 level and its phosphorylation. Knock-down of cofilin-1 reduces viral yields. These findings provide the first evidence that cofilin-1 plays an important role in regulating actin reorganization during IAV assembly and budding. | |||||
書誌情報 |
Biochemical and Biophysical Research Communications 巻 453, 号 4, p. 821-825, 発行日 2014-10-31 |
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出版者 | ||||||
出版者 | Academic Press Inc. | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 0006291X | |||||
DOI | ||||||
関連タイプ | isVersionOf | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1016/j.bbrc.2014.10.036 | |||||
権利 | ||||||
権利情報 | c 2014 Elsevier Inc. | |||||
権利 | ||||||
権利情報 | NOTICE: this is the author’s version of a work that was accepted for publication in Biochemical and Biophysical Research Communications. Changes resulting from the publishing process, such as peer review, editing, corrections, structural formatting, and other quality control mechanisms may not be reflected in this document. Changes may have been made to this work since it was submitted for publication. A definitive version was subsequently published in Biochemical and Biophysical Research Communications, 453, 4, (2014) | |||||
著者版フラグ | ||||||
出版タイプ | AM | |||||
出版タイプResource | http://purl.org/coar/version/c_ab4af688f83e57aa | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Biochemical and Biophysical Research Communications, 453(4), pp.821-825; 2014 |