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Association between alkaline phosphatase and hypertension in a rural Japanese population: The Nagasaki Islands study
http://hdl.handle.net/10069/33596
http://hdl.handle.net/10069/3359698e4effd-d134-4455-87d6-92978ec37641
名前 / ファイル | ライセンス | アクション |
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JPA32_1_10.pdf (213.4 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-09-06 | |||||
タイトル | ||||||
タイトル | Association between alkaline phosphatase and hypertension in a rural Japanese population: The Nagasaki Islands study | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Alkaline Phosphatase | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Cross-sectional Study | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Drinking Status | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Hypertension | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Risk | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Shimizu, Yuji
× Shimizu, Yuji× Nakazato, Mio× Sekita, Takaharu× Kadota, Koichiro× Yamasaki, Hironori× Takamura, Noboru× Aoyagi, Kiyoshi× Kusano, Yosuke× Maeda, Takahiro |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | Background: Although serum alkaline phosphatase (ALP) levels have been associated with hypertension, and ALP is known as an enzyme affected by alcohol consumption, no study has been published on the associations between ALP and the risk of hypertension in relation to drinking status.Methods: We conducted a cross-sectional study of 2,681 participants (837 men and 1,846 women) aged 30 to 89 years undergoing a general health check-up to investigate the associations between ALP and hypertension in relation to drinking status.Results: Of the 2,681 participants, 1,549 (514 men and 1,035 women) were diagnosed with hypertension. A sex difference was observed for the relationship between ALP and hypertension. While no significant association was observed for men, the association was significantly positive for women. The multivariable adjusted odds ratio and 95% coincidence interval (CI) of hypertension per increment of 1-log ALP were 0.95 (95% CI: 0.56 to 1.59) for men and 1.57 (95% CI: 1.07 to 2.33) for women. When this analysis was restricted to nondrinkers, a significantly elevated risk of hypertension was observed for men and remained significant for women; that is, 3.32 (95% CI: 1.38 to 8.02) for men and 1.68 (95% CI: 1.11 to 2.55) for women.Conclusion: ALP is associated with hypertension for both male and female nondrinkers, but not for drinkers. For analyses of associations between ALP and blood pressure, alcohol consumption should thus be considered a potential confounder. | |||||
書誌情報 |
Journal of Physiological Anthropology 巻 32, 号 1, p. 10, 発行日 2013-06-27 |
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出版者 | ||||||
出版者 | 日本生理人類学会 | |||||
出版者別言語 | ||||||
Japan Society of Physiological Anthropology | ||||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 18806805 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1186/1880-6805-32-10 | |||||
権利 | ||||||
権利情報 | © 2013 Yuji et al.; licensee BioMed Central Ltd. | |||||
権利 | ||||||
権利情報 | This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Journal of Physiological Anthropology, 32(1), 10; 2013 |