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Chronic hepatitis B and C co-infection increased all-cause mortality in HAART-naive HIV patients in northern Thailand
http://hdl.handle.net/10069/33881
http://hdl.handle.net/10069/338814d026c6a-0341-463f-a3f2-b9e66bda7f75
名前 / ファイル | ライセンス | アクション |
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Epi&Inf141_1840.pdf (181.0 kB)
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Item type | 学術雑誌論文 / Journal Article(1) | |||||
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公開日 | 2013-10-03 | |||||
タイトル | ||||||
タイトル | Chronic hepatitis B and C co-infection increased all-cause mortality in HAART-naive HIV patients in northern Thailand | |||||
言語 | ||||||
言語 | eng | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | Co-infection | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatitis B | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | hepatitis C | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | mortality | |||||
キーワード | ||||||
主題Scheme | Other | |||||
主題 | resource-limited settings | |||||
資源タイプ | ||||||
資源タイプ識別子 | http://purl.org/coar/resource_type/c_6501 | |||||
資源タイプ | journal article | |||||
著者 |
Tsuchiya, Naho
× Tsuchiya, Naho× Pathipvanich, Panita× Rojanawiwat, Archawin× Wichukchinda, Nuanjun× Koga, Ichiro× Koga, M.× Auwanit, Wattana× Kilgore, Paul Evan× Ariyoshi, Koya× Sawanpanyalert, Pathom |
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抄録 | ||||||
内容記述タイプ | Abstract | |||||
内容記述 | A total of 755 highly active antiretroviral therapy (HAART)-naive HIV-infected patients were enrolled at a government hospital in Thailand from 1 June 2000 to 15 October 2002. Census date of survival was on 31 October 2004 or the date of HAART initiation. Of 700 (92·6%) patients with complete data, the prevalence of hepatitis B virus (HBV) surface antigen and anti-hepatitis C virus (HCV) antibody positivity was 11·9% and 3·3%, respectively. Eight (9·6%) HBV co-infected patients did not have anti-HBV core antibody (anti-HBcAb). During 1166·7 person-years of observation (pyo), 258 (36·9%) patients died [22·1/100 pyo, 95% confidence interval (CI) 16·7-27·8]. HBV and probably HCV co-infection was associated with a higher mortality with adjusted hazard ratios (aHRs) of 1·81 (95% CI 1·30-2·53) and 1·90 (95% CI 0·98-3·69), respectively. Interestingly, HBV co-infection without anti-HBc Ab was strongly associated with death (aHR 6·34, 95% CI 3·99-10·3). The influence of hepatitis co-infection on the natural history of HAART-naive HIV patients requires greater attention. | |||||
書誌情報 |
Epidemiology and Infection 巻 141, 号 9, p. 1840-1848, 発行日 2013-09 |
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出版者 | ||||||
出版者 | Cambridge University Press | |||||
ISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 09502688 | |||||
EISSN | ||||||
収録物識別子タイプ | ISSN | |||||
収録物識別子 | 14694409 | |||||
DOI | ||||||
関連タイプ | isIdenticalTo | |||||
識別子タイプ | DOI | |||||
関連識別子 | 10.1017/S0950268812002397 | |||||
権利 | ||||||
権利情報 | © Cambridge University Press 2012 The online version of this article is published within an Open Access environment subject to the conditions of the Creative Commons Attribution-NonCommercial-ShareAlike licence <http://creativecommons.org/licenses/by-nc-sa/2.5/>. The written permission of Cambridge University Press must be obtained for commercial re-use. DOI: http://dx.doi.org/10.1017/S0950268812002397 (About DOI), Published online: 01 November 2012 | |||||
著者版フラグ | ||||||
出版タイプ | VoR | |||||
出版タイプResource | http://purl.org/coar/version/c_970fb48d4fbd8a85 | |||||
引用 | ||||||
内容記述タイプ | Other | |||||
内容記述 | Epidemiology and Infection, 141(9), pp.1840-1848; 2013 |